Biological process

PCP pathway, Wnt receptor signaling pathway, planar cell polarity pathway, Wnt receptor signalling pathway, planar cell polarity pathway, Wnt-activated signaling pathway, planar cell polarity pathway, planar cell polarity pathway

A type of non-canonical Wnt signaling pathway in which Wnt binding to its receptor on the surface of a target cell results in the activation small G proteins such as Rho, Rac, and Cdc42 which, in turn activate effectors, including C-Jun N-terminal kinase (JNK) and Rho kinase (Rok). The signaling ends with change in the transcription of target genes and/or reorganisation of the cytoskeleton.

Wnt-JNK signaling pathway, Wnt-PCP signaling pathway, non-canonical Wnt signaling pathway