I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 22% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 22% ± 5% |
Insufficient scRNA-seq data for expression of CELSR3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 98% | 4488.34 | 2600 / 2642 | 92% | 14.65 | 647 / 705 |
| intestine | 61% | 296.39 | 585 / 966 | 76% | 5.59 | 403 / 527 |
| stomach | 61% | 272.16 | 219 / 359 | 76% | 5.86 | 216 / 286 |
| uterus | 58% | 254.44 | 99 / 170 | 76% | 7.13 | 350 / 459 |
| adrenal gland | 44% | 342.09 | 114 / 258 | 70% | 12.32 | 162 / 230 |
| pancreas | 42% | 199.86 | 139 / 328 | 71% | 4.80 | 126 / 178 |
| skin | 73% | 362.42 | 1313 / 1809 | 36% | 2.23 | 170 / 472 |
| lung | 55% | 225.39 | 317 / 578 | 53% | 3.33 | 608 / 1155 |
| ureter | 0% | 0 | 0 / 0 | 100% | 2.25 | 1 / 1 |
| breast | 47% | 206.73 | 216 / 459 | 51% | 3.84 | 575 / 1118 |
| ovary | 54% | 231.76 | 97 / 180 | 36% | 1.62 | 155 / 430 |
| bladder | 19% | 68.76 | 4 / 21 | 70% | 5.52 | 353 / 504 |
| spleen | 88% | 455.13 | 213 / 241 | 0% | 0 | 0 / 0 |
| esophagus | 11% | 40.17 | 160 / 1445 | 72% | 7.90 | 131 / 183 |
| prostate | 50% | 188.37 | 123 / 245 | 23% | 1.49 | 114 / 502 |
| thymus | 70% | 292.55 | 456 / 653 | 3% | 0.12 | 17 / 605 |
| tonsil | 0% | 0 | 0 / 0 | 71% | 5.85 | 32 / 45 |
| blood vessel | 57% | 238.42 | 767 / 1335 | 0% | 0 | 0 / 0 |
| liver | 4% | 14.08 | 9 / 226 | 25% | 1.05 | 100 / 406 |
| adipose | 28% | 113.88 | 339 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 28% | 1.39 | 8 / 29 |
| peripheral blood | 27% | 173.86 | 253 / 929 | 0% | 0 | 0 / 0 |
| kidney | 17% | 74.07 | 15 / 89 | 7% | 0.29 | 63 / 901 |
| heart | 1% | 4.61 | 11 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.09 | 1 / 80 |
| muscle | 1% | 5.28 | 9 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0036514 | Biological process | dopaminergic neuron axon guidance |
| GO_0060071 | Biological process | Wnt signaling pathway, planar cell polarity pathway |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0007156 | Biological process | homophilic cell adhesion via plasma membrane adhesion molecules |
| GO_0098609 | Biological process | cell-cell adhesion |
| GO_0036515 | Biological process | serotonergic neuron axon guidance |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0004930 | Molecular function | G protein-coupled receptor activity |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CELSR3 |
| Protein name | Alternative protein CELSR3 Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2) |
| Synonyms | MEGF2 FMI1 EGFL1 CDHF11 KIAA0812 |
| Description | FUNCTION: Receptor that may have an important role in cell/cell signaling during nervous system formation. |
| Accessions | ENST00000164024.5 [Q9NYQ7-1] Q9NYQ7 L0R6E8 |
