WNT11 | OmnibusX

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of WNT11 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	98%	399.35	323 / 328	70%	25.72	124 / 178
prostate	87%	347.74	214 / 245	67%	9.17	335 / 502
ovary	67%	292.80	121 / 180	80%	33.67	346 / 430
breast	99%	1726.10	455 / 459	44%	8.45	491 / 1118
adrenal gland	100%	1456.09	258 / 258	38%	8.55	88 / 230
intestine	67%	221.37	651 / 966	69%	26.85	365 / 527
lung	93%	462.77	535 / 578	40%	10.16	457 / 1155
uterus	83%	295.81	141 / 170	46%	14.02	209 / 459
thymus	99%	1363.05	647 / 653	22%	1.88	136 / 605
bladder	71%	294.48	15 / 21	44%	11.26	224 / 504
esophagus	51%	220.27	740 / 1445	50%	10.53	91 / 183
ureter	0%	0	0 / 0	100%	10.54	1 / 1
adipose	100%	2586.07	1203 / 1204	0%	0	0 / 0
liver	62%	270.73	139 / 226	37%	3.74	152 / 406
muscle	89%	411.34	716 / 803	0%	0	0 / 0
heart	87%	368.30	752 / 861	0%	0	0 / 0
blood vessel	84%	499.55	1128 / 1335	0%	0	0 / 0
skin	68%	404.82	1234 / 1809	13%	1.18	63 / 472
stomach	22%	63.52	78 / 359	59%	26.63	168 / 286
spleen	71%	249.58	171 / 241	0%	0	0 / 0
eye	0%	0	0 / 0	45%	2.50	36 / 80
kidney	18%	60.55	16 / 89	11%	1.44	97 / 901
brain	15%	30.32	390 / 2642	3%	0.38	23 / 705
lymph node	0%	0	0 / 0	17%	6.17	5 / 29
tonsil	0%	0	0 / 0	13%	1.79	6 / 45
peripheral blood	9%	34.47	79 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0071300	Biological process	cellular response to retinoic acid
GO_0060197	Biological process	cloacal septation
GO_0048844	Biological process	artery morphogenesis
GO_0001837	Biological process	epithelial to mesenchymal transition
GO_0045199	Biological process	maintenance of epithelial cell apical/basal polarity
GO_0003151	Biological process	outflow tract morphogenesis
GO_0071260	Biological process	cellular response to mechanical stimulus
GO_0060775	Biological process	planar cell polarity pathway involved in gastrula mediolateral intercalation
GO_0043547	Biological process	positive regulation of GTPase activity
GO_0048341	Biological process	paraxial mesoderm formation
GO_0003402	Biological process	planar cell polarity pathway involved in axis elongation
GO_0051496	Biological process	positive regulation of stress fiber assembly
GO_0060028	Biological process	convergent extension involved in axis elongation
GO_0072201	Biological process	negative regulation of mesenchymal cell proliferation
GO_0007223	Biological process	Wnt signaling pathway, calcium modulating pathway
GO_0001649	Biological process	osteoblast differentiation
GO_0061053	Biological process	somite development
GO_0090272	Biological process	negative regulation of fibroblast growth factor production
GO_0007165	Biological process	signal transduction
GO_0062009	Biological process	secondary palate development
GO_0060675	Biological process	ureteric bud morphogenesis
GO_0003138	Biological process	primary heart field specification
GO_0048570	Biological process	notochord morphogenesis
GO_0034394	Biological process	protein localization to cell surface
GO_0090090	Biological process	negative regulation of canonical Wnt signaling pathway
GO_0060070	Biological process	canonical Wnt signaling pathway
GO_1904037	Biological process	positive regulation of epithelial cell apoptotic process
GO_2000647	Biological process	negative regulation of stem cell proliferation
GO_0031667	Biological process	response to nutrient levels
GO_0030182	Biological process	neuron differentiation
GO_0003283	Biological process	atrial septum development
GO_0061101	Biological process	neuroendocrine cell differentiation
GO_0045165	Biological process	cell fate commitment
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0048706	Biological process	embryonic skeletal system development
GO_0030325	Biological process	adrenal gland development
GO_0010463	Biological process	mesenchymal cell proliferation
GO_0030282	Biological process	bone mineralization
GO_0070830	Biological process	bicellular tight junction assembly
GO_0060412	Biological process	ventricular septum morphogenesis
GO_1904019	Biological process	epithelial cell apoptotic process
GO_0090037	Biological process	positive regulation of protein kinase C signaling
GO_0030336	Biological process	negative regulation of cell migration
GO_0060071	Biological process	Wnt signaling pathway, planar cell polarity pathway
GO_0032915	Biological process	positive regulation of transforming growth factor beta2 production
GO_0006468	Biological process	protein phosphorylation
GO_0060484	Biological process	lung-associated mesenchyme development
GO_0003139	Biological process	secondary heart field specification
GO_0072177	Biological process	mesonephric duct development
GO_0045892	Biological process	negative regulation of DNA-templated transcription
GO_0061037	Biological process	negative regulation of cartilage development
GO_0030308	Biological process	negative regulation of cell growth
GO_0072089	Biological process	stem cell proliferation
GO_0005615	Cellular component	extracellular space
GO_0005576	Cellular component	extracellular region
GO_0031012	Cellular component	extracellular matrix
GO_0005737	Cellular component	cytoplasm
GO_0005109	Molecular function	frizzled binding
GO_0005096	Molecular function	GTPase activator activity
GO_0030295	Molecular function	protein kinase activator activity
GO_0005515	Molecular function	protein binding
GO_0005125	Molecular function	cytokine activity

Gene name	WNT11
Protein name	Protein Wnt-11
Synonyms
Description	FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
Accessions	ENST00000322563.8 O96014

WNT11 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review