Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell | 24 studies | 41% ± 20% | |
| capillary endothelial cell | 9 studies | 55% ± 16% | |
| vein endothelial cell | 9 studies | 33% ± 16% | |
| endothelial cell of artery | 8 studies | 42% ± 20% | |
| endothelial cell of vascular tree | 7 studies | 30% ± 13% | |
| glomerular endothelial cell | 3 studies | 37% ± 5% | |
| mesothelial cell | 3 studies | 52% ± 6% |
Insufficient scRNA-seq data for expression of TMEM88 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adrenal gland | 100% | 606.53 | 258 / 258 | 99% | 29.73 | 228 / 230 |
| kidney | 100% | 885.62 | 89 / 89 | 99% | 36.72 | 892 / 901 |
| prostate | 100% | 542.75 | 244 / 245 | 99% | 14.76 | 499 / 502 |
| thymus | 100% | 1142.03 | 653 / 653 | 99% | 29.64 | 598 / 605 |
| bladder | 100% | 489.43 | 21 / 21 | 89% | 9.67 | 449 / 504 |
| intestine | 100% | 423.57 | 962 / 966 | 85% | 6.81 | 450 / 527 |
| brain | 85% | 185.30 | 2239 / 2642 | 100% | 14.07 | 704 / 705 |
| stomach | 100% | 383.22 | 358 / 359 | 85% | 9.77 | 242 / 286 |
| esophagus | 86% | 461.00 | 1242 / 1445 | 91% | 7.68 | 167 / 183 |
| lung | 98% | 433.98 | 564 / 578 | 79% | 7.28 | 915 / 1155 |
| pancreas | 77% | 145.62 | 254 / 328 | 98% | 13.44 | 175 / 178 |
| breast | 100% | 760.17 | 458 / 459 | 74% | 6.29 | 828 / 1118 |
| uterus | 99% | 676.68 | 168 / 170 | 71% | 11.44 | 328 / 459 |
| ovary | 80% | 226.13 | 144 / 180 | 87% | 10.86 | 374 / 430 |
| liver | 31% | 60.96 | 69 / 226 | 91% | 8.56 | 368 / 406 |
| skin | 24% | 39.60 | 432 / 1809 | 83% | 8.20 | 392 / 472 |
| ureter | 0% | 0 | 0 / 0 | 100% | 9.88 | 1 / 1 |
| heart | 100% | 1006.98 | 859 / 861 | 0% | 0 | 0 / 0 |
| spleen | 100% | 502.93 | 240 / 241 | 0% | 0 | 0 / 0 |
| adipose | 99% | 1005.25 | 1194 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 97% | 355.54 | 782 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 94% | 6.95 | 75 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 76% | 5.26 | 22 / 29 |
| blood vessel | 68% | 257.64 | 906 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 57% | 283.39 | 526 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 56% | 2.36 | 25 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0016055 | Biological process | Wnt signaling pathway |
| GO_0072659 | Biological process | protein localization to plasma membrane |
| GO_0050821 | Biological process | protein stabilization |
| GO_0090090 | Biological process | negative regulation of canonical Wnt signaling pathway |
| GO_0005829 | Cellular component | cytosol |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0030165 | Molecular function | PDZ domain binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | TMEM88 |
| Protein name | Transmembrane protein 88 |
| Synonyms | TMEM88A |
| Description | FUNCTION: Inhibits the Wnt/beta-catenin signaling pathway. Crucial for heart development and acts downstream of GATA factors in the pre-cardiac mesoderm to specify lineage commitment of cardiomyocyte development. . |
| Accessions | ENST00000301599.7 Q6PEY1 ENST00000574668.1 I3L2J3 |
