Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 6 studies | 26% ± 10% | |
| fibroblast | 5 studies | 22% ± 6% | |
| myofibroblast cell | 4 studies | 25% ± 7% | |
| endothelial cell | 3 studies | 20% ± 6% | |
| GABAergic neuron | 3 studies | 33% ± 11% | |
| oligodendrocyte precursor cell | 3 studies | 21% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 20% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 7600.58 | 245 / 245 | 98% | 32.50 | 494 / 502 |
| thymus | 100% | 10432.62 | 653 / 653 | 98% | 76.08 | 591 / 605 |
| pancreas | 99% | 2588.00 | 325 / 328 | 97% | 28.00 | 173 / 178 |
| breast | 100% | 4715.19 | 459 / 459 | 90% | 30.02 | 1011 / 1118 |
| intestine | 98% | 5001.94 | 944 / 966 | 84% | 34.94 | 441 / 527 |
| bladder | 100% | 8354.57 | 21 / 21 | 81% | 43.94 | 410 / 504 |
| lung | 100% | 5556.61 | 576 / 578 | 77% | 25.08 | 893 / 1155 |
| stomach | 97% | 3214.37 | 348 / 359 | 80% | 33.29 | 228 / 286 |
| ovary | 99% | 3552.63 | 179 / 180 | 76% | 23.15 | 328 / 430 |
| brain | 82% | 7822.24 | 2178 / 2642 | 91% | 32.49 | 641 / 705 |
| uterus | 99% | 8706.25 | 168 / 170 | 74% | 32.95 | 338 / 459 |
| adrenal gland | 100% | 3830.34 | 257 / 258 | 73% | 29.00 | 167 / 230 |
| kidney | 100% | 5540.21 | 89 / 89 | 72% | 17.96 | 649 / 901 |
| esophagus | 91% | 3448.79 | 1316 / 1445 | 49% | 9.01 | 89 / 183 |
| skin | 81% | 2136.19 | 1469 / 1809 | 36% | 8.97 | 171 / 472 |
| liver | 56% | 780.37 | 126 / 226 | 49% | 8.24 | 199 / 406 |
| ureter | 0% | 0 | 0 / 0 | 100% | 85.88 | 1 / 1 |
| adipose | 100% | 4464.64 | 1201 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 6065.81 | 240 / 241 | 0% | 0 | 0 / 0 |
| heart | 99% | 5145.87 | 855 / 861 | 0% | 0 | 0 / 0 |
| muscle | 99% | 3640.95 | 795 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 82% | 2756.14 | 1090 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 65% | 10.11 | 52 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 53% | 16.34 | 24 / 45 |
| peripheral blood | 0% | 6.35 | 3 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007165 | Biological process | signal transduction |
| GO_0016055 | Biological process | Wnt signaling pathway |
| GO_0009887 | Biological process | animal organ morphogenesis |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0090090 | Biological process | negative regulation of canonical Wnt signaling pathway |
| GO_0005615 | Cellular component | extracellular space |
| GO_0016604 | Cellular component | nuclear body |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005925 | Cellular component | focal adhesion |
| GO_0005667 | Cellular component | transcription regulator complex |
| GO_0005634 | Cellular component | nucleus |
| GO_0003714 | Molecular function | transcription corepressor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | TLE2 |
| Protein name | TLE family member 2, transcriptional corepressor Transducin-like enhancer protein 2 (Enhancer of split groucho-like protein 2) (ESG2) |
| Synonyms | |
| Description | FUNCTION: Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity). . |
| Accessions | K7ESD8 ENST00000590536.5 ENST00000587137.5 ENST00000586422.5 ENST00000426948.6 [Q04725-3] ENST00000591529.5 [Q04725-3] ENST00000591457.5 K7EPD4 K7EJR7 K7EPF3 K7EK93 ENST00000592584.1 K7EMK7 ENST00000262953.11 [Q04725-1] ENST00000589364.5 Q04725 ENST00000443826.7 [Q04725-2] |