Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 5 studies | 22% ± 7% | |
epithelial cell | 4 studies | 19% ± 4% | |
microglial cell | 3 studies | 20% ± 3% | |
precursor B cell | 3 studies | 17% ± 0% | |
endothelial cell of lymphatic vessel | 3 studies | 42% ± 33% | |
GABAergic neuron | 3 studies | 28% ± 7% | |
glutamatergic neuron | 3 studies | 35% ± 7% | |
neuron | 3 studies | 22% ± 1% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 3 studies | 24% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adrenal gland | 100% | 3613.39 | 258 / 258 | 100% | 27.55 | 230 / 230 |
bladder | 100% | 3707.95 | 21 / 21 | 100% | 20.55 | 504 / 504 |
esophagus | 100% | 3184.42 | 1445 / 1445 | 100% | 10.97 | 183 / 183 |
lung | 100% | 3722.71 | 578 / 578 | 100% | 15.33 | 1155 / 1155 |
prostate | 100% | 4224.76 | 245 / 245 | 100% | 15.04 | 502 / 502 |
uterus | 100% | 4764.44 | 170 / 170 | 100% | 15.53 | 459 / 459 |
skin | 100% | 2664.09 | 1808 / 1809 | 100% | 18.99 | 472 / 472 |
thymus | 100% | 3733.68 | 653 / 653 | 100% | 20.85 | 604 / 605 |
breast | 100% | 3488.49 | 459 / 459 | 100% | 13.82 | 1116 / 1118 |
stomach | 100% | 1919.63 | 358 / 359 | 100% | 11.73 | 286 / 286 |
intestine | 100% | 3596.07 | 966 / 966 | 100% | 14.14 | 525 / 527 |
kidney | 100% | 2937.08 | 89 / 89 | 99% | 16.32 | 894 / 901 |
ovary | 100% | 4543.76 | 180 / 180 | 99% | 10.62 | 425 / 430 |
pancreas | 98% | 1355.88 | 320 / 328 | 100% | 17.92 | 178 / 178 |
liver | 99% | 1371.96 | 224 / 226 | 98% | 9.00 | 398 / 406 |
brain | 95% | 1984.76 | 2518 / 2642 | 100% | 19.51 | 705 / 705 |
adipose | 100% | 3203.35 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 17.95 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 16.06 | 29 / 29 |
spleen | 100% | 4766.75 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 10.44 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 17.68 | 1 / 1 |
blood vessel | 100% | 2942.69 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 100% | 1837.43 | 857 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 98% | 2403.29 | 915 / 929 | 0% | 0 | 0 / 0 |
muscle | 97% | 1237.97 | 778 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007165 | Biological process | signal transduction |
GO_0060218 | Biological process | hematopoietic stem cell differentiation |
GO_0030217 | Biological process | T cell differentiation |
GO_0016055 | Biological process | Wnt signaling pathway |
GO_0042098 | Biological process | T cell proliferation |
GO_0006898 | Biological process | receptor-mediated endocytosis |
GO_0070231 | Biological process | T cell apoptotic process |
GO_0090090 | Biological process | negative regulation of canonical Wnt signaling pathway |
GO_0005886 | Cellular component | plasma membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0004888 | Molecular function | transmembrane signaling receptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | LMBR1L |
Protein name | Limb development membrane protein 1 like Limb region 1 homolog (Mouse)-like, isoform CRA_e (Limb region 1-like protein-like isoform 1) Protein LMBR1L (Limb region 1 protein homolog-like) (Lipocalin-1-interacting membrane receptor) (LIMR) Limb region 1-like protein-like isoform 3 Limb region 1-like protein-like isoform 5 Limb region 1-like protein-like isoform 2 Limb region 1 homolog (Mouse)-like, isoform CRA_b (Limb region 1-like protein-like isoform 4) |
Synonyms | hCG_2010766 LIMR KIAA1174 UNQ458/PRO783 |
Description | FUNCTION: Plays an essential role in lymphocyte development by negatively regulating the canonical Wnt signaling pathway (By similarity). In association with UBAC2 and E3 ubiquitin-protein ligase AMFR, promotes the ubiquitin-mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6 (By similarity). LMBR1L stabilizes the beta-catenin destruction complex that is required for regulating CTNNB1 levels (By similarity). Acts as a LCN1 receptor and can mediate its endocytosis . . |
Accessions | F8W0N6 ENST00000551782.5 ENST00000550137.5 E7ESX7 A0A0S2Z5M5 ENST00000547670.5 ENST00000549296.1 ENST00000551169.5 F8VZU8 ENST00000547382.5 [Q6UX01-3] A0A0S2Z5S6 ENST00000552449.1 A0A024R0Y9 H0YHY8 ENST00000267102.13 [Q6UX01-1] H0YI83 F8VYZ9 H0YIX2 ENST00000417750.5 A0A0S2Z5F8 ENST00000457164.6 ENST00000547698.5 ENST00000547675.5 A0A0S2Z6E3 ENST00000553040.5 F8WE63 F8W054 Q6UX01 ENST00000551854.5 ENST00000550815.1 F8VVE2 H0YHZ2 F8VPB1 |