VAX2 | OmnibusX

Name	Number of supported studies	Average coverage
retinal cone cell	3 studies	35% ± 9%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of VAX2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	99%	151.27	2614 / 2642	96%	11.92	675 / 705
skin	98%	66.21	1764 / 1809	85%	3.69	403 / 472
ovary	98%	39.93	177 / 180	83%	5.30	355 / 430
breast	99%	74.62	453 / 459	65%	2.61	726 / 1118
uterus	98%	83.39	166 / 170	65%	4.16	297 / 459
prostate	96%	45.58	236 / 245	52%	1.49	262 / 502
adrenal gland	86%	23.31	222 / 258	60%	4.22	139 / 230
lung	87%	34.54	505 / 578	49%	1.48	562 / 1155
esophagus	85%	27.20	1228 / 1445	46%	1.59	85 / 183
pancreas	98%	41.78	321 / 328	23%	0.49	41 / 178
bladder	81%	26.05	17 / 21	34%	1.11	173 / 504
eye	0%	0	0 / 0	99%	4.81	79 / 80
adipose	98%	57.99	1178 / 1204	0%	0	0 / 0
kidney	83%	21.38	74 / 89	9%	0.28	82 / 901
intestine	82%	28.70	791 / 966	9%	0.21	45 / 527
blood vessel	81%	24.19	1078 / 1335	0%	0	0 / 0
heart	73%	20.60	629 / 861	0%	0	0 / 0
muscle	63%	15.19	508 / 803	0%	0	0 / 0
thymus	54%	10.31	350 / 653	2%	0.04	12 / 605
stomach	34%	7.94	122 / 359	10%	0.26	30 / 286
tonsil	0%	0	0 / 0	24%	0.64	11 / 45
liver	4%	0.58	9 / 226	16%	0.41	63 / 406
spleen	2%	0.35	6 / 241	0%	0	0 / 0
peripheral blood	0%	0.03	2 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007601	Biological process	visual perception
GO_0030900	Biological process	forebrain development
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0060041	Biological process	retina development in camera-type eye
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0009950	Biological process	dorsal/ventral axis specification
GO_0007409	Biological process	axonogenesis
GO_0030182	Biological process	neuron differentiation
GO_0007417	Biological process	central nervous system development
GO_0007420	Biological process	brain development
GO_0016055	Biological process	Wnt signaling pathway
GO_0048048	Biological process	embryonic eye morphogenesis
GO_0007398	Biological process	ectoderm development
GO_0005737	Cellular component	cytoplasm
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001227	Molecular function	DNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_1990837	Molecular function	sequence-specific double-stranded DNA binding
GO_0003700	Molecular function	DNA-binding transcription factor activity
GO_0031490	Molecular function	chromatin DNA binding
GO_0001162	Molecular function	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
GO_0005515	Molecular function	protein binding

Gene name	VAX2
Protein name	Ventral anterior homeobox 2
Synonyms
Description	FUNCTION: Transcription factor that may function in dorsoventral specification of the forebrain. Regulates the expression of Wnt signaling antagonists including the expression of a truncated TCF7L2 isoform that cannot bind CTNNB1 and acts therefore as a potent dominant-negative Wnt antagonist. Plays a crucial role in eye development and, in particular, in the specification of the ventral optic vesicle (By similarity). May be a regulator of axial polarization in the retina. .
Accessions	ENST00000646783.1 Q9UIW0 ENST00000432367.6 F1T0K5 C9J5E3 A0A2R8Y6H5 ENST00000234392.3

VAX2 report