dorsal/ventral axis specification

I. Involved cell types

Genes
Cell types
No. of supported studies
Group 1
VAX2
retinal cone cell
4 studies
Group 2
WNT3AXIN1CAPRIN2BMPR1ACTNNB1
dopaminergic neuron
5 studies
Group 3
PAX6
neuronglial cell
29 studies
Group 4
SFRP1MDFI
connective tissue cellepithelial cell
5 studies

II. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1WNT3-SFRP1WNT3_HUMAN - SFRP1_HUMANLigand-LigandSignaling by WNT inhibition
2WNT8A-SFRP1WNT8A_HUMAN - SFRP1_HUMANLigand-LigandSignaling by WNT inhibition

III. Literature review

[source]
Namedorsal/ventral axis specification
IDGO_0009950
collection_id

Biological process

Exact synonym

dorsal-ventral axis specification, dorsoventral axis specification

Related synonym

dorsal/ventral axis determination

Description

The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.

External URL
Genes
AXIN1MDFISFRP1BMPR1AAXIN2WNT3CTNNB1PAX6CAPRIN2WNT8AVAX2