Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| fibroblast | 11 studies | 35% ± 13% | |
| connective tissue cell | 6 studies | 58% ± 19% | |
| myofibroblast cell | 6 studies | 42% ± 20% | |
| smooth muscle cell | 4 studies | 28% ± 10% | |
| mesothelial cell | 3 studies | 26% ± 9% | |
| neural crest cell | 3 studies | 28% ± 4% | |
| pericyte | 3 studies | 23% ± 5% | |
| basal cell | 3 studies | 22% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 1178.83 | 576 / 578 | 84% | 43.14 | 968 / 1155 |
| uterus | 92% | 484.54 | 156 / 170 | 89% | 102.07 | 407 / 459 |
| bladder | 95% | 851.62 | 20 / 21 | 85% | 64.16 | 427 / 504 |
| breast | 99% | 1504.41 | 454 / 459 | 73% | 47.27 | 821 / 1118 |
| ovary | 100% | 935.71 | 180 / 180 | 65% | 35.21 | 278 / 430 |
| esophagus | 58% | 964.59 | 836 / 1445 | 95% | 54.74 | 173 / 183 |
| brain | 63% | 190.53 | 1652 / 2642 | 89% | 76.87 | 627 / 705 |
| prostate | 99% | 965.09 | 243 / 245 | 49% | 25.26 | 245 / 502 |
| thymus | 89% | 302.38 | 583 / 653 | 50% | 26.00 | 302 / 605 |
| stomach | 60% | 214.65 | 214 / 359 | 75% | 23.82 | 215 / 286 |
| pancreas | 25% | 78.69 | 83 / 328 | 92% | 47.58 | 164 / 178 |
| intestine | 37% | 111.28 | 361 / 966 | 74% | 23.79 | 392 / 527 |
| skin | 73% | 634.14 | 1312 / 1809 | 37% | 29.73 | 176 / 472 |
| ureter | 0% | 0 | 0 / 0 | 100% | 92.83 | 1 / 1 |
| adipose | 99% | 1458.60 | 1188 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 52.66 | 43 / 45 |
| adrenal gland | 80% | 236.74 | 206 / 258 | 7% | 3.22 | 15 / 230 |
| kidney | 65% | 269.28 | 58 / 89 | 5% | 3.39 | 48 / 901 |
| heart | 50% | 215.05 | 428 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 48% | 220.69 | 643 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 30% | 7.22 | 24 / 80 |
| liver | 6% | 21.83 | 13 / 226 | 15% | 6.27 | 62 / 406 |
| muscle | 3% | 7.31 | 23 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 1.30 | 1 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| GO_0030178 | Biological process | negative regulation of Wnt signaling pathway |
| GO_0048704 | Biological process | embryonic skeletal system morphogenesis |
| GO_0042994 | Biological process | cytoplasmic sequestering of transcription factor |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0009950 | Biological process | dorsal/ventral axis specification |
| GO_0043392 | Biological process | negative regulation of DNA binding |
| GO_0060707 | Biological process | trophoblast giant cell differentiation |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0008134 | Molecular function | transcription factor binding |
| GO_0140416 | Molecular function | transcription regulator inhibitor activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | MDFI |
| Protein name | MyoD family inhibitor (Myogenic repressor I-mf) MyoD family inhibitor |
| Synonyms | |
| Description | FUNCTION: Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important role in trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by interacting directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways (By similarity). . |
| Accessions | B1AKC1 ENST00000373051.6 B1AKB8 B1AKC0 ENST00000446650.1 B1AKB6 Q99750 ENST00000419164.6 ENST00000432027.5 B1AKB7 B1AKB9 ENST00000373050.8 ENST00000435476.1 ENST00000441667.5 ENST00000230321.11 |
