CAPRIN2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0090263Biological processpositive regulation of canonical Wnt signaling pathway
GO_0061003Biological processpositive regulation of dendritic spine morphogenesis
GO_0009950Biological processdorsal/ventral axis specification
GO_0050775Biological processpositive regulation of dendrite morphogenesis
GO_0030154Biological processcell differentiation
GO_0017148Biological processnegative regulation of translation
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0030308Biological processnegative regulation of cell growth
GO_0043235Cellular componentreceptor complex
GO_0005886Cellular componentplasma membrane
GO_0005739Cellular componentmitochondrion
GO_0005813Cellular componentcentrosome
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005102Molecular functionsignaling receptor binding
GO_0046872Molecular functionmetal ion binding
GO_0003723Molecular functionRNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCAPRIN2
Protein nameCaprin family member 2
Alternative protein CAPRIN2
Caprin-2 (C1q domain-containing protein 1) (Cytoplasmic activation/proliferation-associated protein 2) (Gastric cancer multidrug resistance-associated protein) (Protein EEG-1) (RNA granule protein 140)
SynonymsEEG1
C1QDC1
RNG140
KIAA1873
DescriptionFUNCTION: Promotes phosphorylation of the Wnt coreceptor LRP6, leading to increased activity of the canonical Wnt signaling pathway . Facilitates constitutive LRP6 phosphorylation by CDK14/CCNY during G2/M stage of the cell cycle, which may potentiate cells for Wnt signaling . May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons (By similarity). Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation . May be involved in apoptosis . .

AccessionsA0A8I5KUY8
A0A8Q3SHP6
A0A8Q3WKC4
F5H142
A0A8Q3SHW1
ENST00000548676.5
ENST00000687797.1 [Q6IMN6-1]
ENST00000692932.1
ENST00000541765.5
ENST00000695369.1
A0A8Q3SHE9
ENST00000695370.1
ENST00000686317.1
ENST00000694880.1
ENST00000695327.1
F5GXI7
ENST00000417045.5 [Q6IMN6-3]
ENST00000688163.1
H0YID4
ENST00000695371.1
A0A8Q3WKF3
ENST00000540584.2
A0A8I5KUX4
A0A8Q3WKE6
ENST00000690233.1
ENST00000695402.1
ENST00000695328.1
ENST00000690097.1
H0YGG3
L8E8S3
F5GYA1
A0A8Q3WLH0
H3BM22
A0A8I5KPA6
A0A8I5KRN0
A0A8I5KZC0
F5GZX3
ENST00000695372.1
ENST00000695326.1
ENST00000689016.1
ENST00000695374.1
ENST00000537108.5
ENST00000684863.1 [Q6IMN6-4]
ENST00000433722.6
ENST00000543380.5
ENST00000298892.9 [Q6IMN6-2]
ENST00000537553.5
A0A8Q3SHV1
ENST00000690126.1
ENST00000540436.6
ENST00000695329.1
A0A8I5KSM9
F5H5J8
ENST00000695398.1
ENST00000542550.6
A0A8Q3SHS5
ENST00000695330.1
ENST00000395805.6 [Q6IMN6-10]
ENST00000695400.1
A0A8Q3WKE7
ENST00000454014.6 [Q6IMN6-5]
ENST00000695373.1
Q6IMN6