AMER3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of AMER3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of AMER3 at tissue level.

III. Associated gene sets

GO_0016055Biological processWnt signaling pathway
GO_0060828Biological processregulation of canonical Wnt signaling pathway
GO_0005886Cellular componentplasma membrane
GO_0005546Molecular functionphosphatidylinositol-4,5-bisphosphate binding
GO_0005515Molecular functionprotein binding
GO_0008013Molecular functionbeta-catenin binding

IV. Literature review

[source]
Gene nameAMER3
Protein nameAPC membrane recruitment protein 3
APC membrane recruitment protein 3 (Amer3) (Protein FAM123C)
SynonymsFAM123C
DescriptionFUNCTION: Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity). .

AccessionsENST00000458606.6
C9JS07
ENST00000431758.2
ENST00000321420.5
C9J4B8
Q8N944