Insufficient scRNA-seq data for expression of TMEM198 at single-cell level.
Insufficient scRNA-seq data for expression of TMEM198 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 907.62 | 2632 / 2642 | 100% | 30.89 | 703 / 705 |
| prostate | 100% | 419.48 | 245 / 245 | 96% | 8.31 | 481 / 502 |
| adrenal gland | 100% | 684.12 | 258 / 258 | 94% | 30.67 | 217 / 230 |
| pancreas | 100% | 631.81 | 328 / 328 | 88% | 6.95 | 157 / 178 |
| skin | 79% | 148.49 | 1429 / 1809 | 91% | 11.08 | 430 / 472 |
| thymus | 100% | 394.79 | 650 / 653 | 68% | 3.54 | 409 / 605 |
| bladder | 100% | 366.57 | 21 / 21 | 66% | 4.79 | 335 / 504 |
| liver | 96% | 208.34 | 216 / 226 | 70% | 6.45 | 285 / 406 |
| breast | 97% | 286.54 | 443 / 459 | 67% | 5.60 | 748 / 1118 |
| kidney | 99% | 328.72 | 88 / 89 | 64% | 4.77 | 577 / 901 |
| intestine | 99% | 270.11 | 957 / 966 | 62% | 5.00 | 326 / 527 |
| ovary | 100% | 1305.91 | 180 / 180 | 57% | 4.90 | 247 / 430 |
| stomach | 100% | 339.97 | 358 / 359 | 54% | 4.85 | 154 / 286 |
| uterus | 99% | 390.72 | 169 / 170 | 50% | 4.97 | 230 / 459 |
| lung | 92% | 309.19 | 533 / 578 | 56% | 4.18 | 647 / 1155 |
| esophagus | 95% | 319.46 | 1378 / 1445 | 40% | 2.53 | 74 / 183 |
| eye | 0% | 0 | 0 / 0 | 100% | 15.46 | 80 / 80 |
| adipose | 97% | 241.67 | 1166 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 95% | 200.26 | 230 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 95% | 211.81 | 1274 / 1335 | 0% | 0 | 0 / 0 |
| heart | 92% | 254.10 | 792 / 861 | 0% | 0 | 0 / 0 |
| muscle | 56% | 134.67 | 451 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 38% | 2.69 | 11 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 29% | 2.91 | 13 / 45 |
| peripheral blood | 18% | 38.40 | 165 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0016055 | Biological process | Wnt signaling pathway |
| GO_0090263 | Biological process | positive regulation of canonical Wnt signaling pathway |
| GO_0031410 | Cellular component | cytoplasmic vesicle |
| GO_0005886 | Cellular component | plasma membrane |
| Gene name | TMEM198 |
| Protein name | Transmembrane protein 198 |
| Synonyms | |
| Description | FUNCTION: Promotes LRP6 phosphorylation by casein kinases and thereby plays a role in Wnt signaling. May be a membrane scaffold protein involved in the self-aggregation of LRP6 to further enhance its activity. . |
| Accessions | C9JFY7 ENST00000421791.1 C9JXI5 ENST00000373883.4 ENST00000451952.1 ENST00000344458.6 Q66K66 |