VTI1A | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	25 studies	43% ± 14%	Explore
astrocyte	17 studies	40% ± 19%	Explore
oligodendrocyte	15 studies	39% ± 15%	Explore
microglial cell	14 studies	50% ± 14%	Explore
oligodendrocyte precursor cell	13 studies	38% ± 15%	Explore
glutamatergic neuron	12 studies	56% ± 26%	Explore
macrophage	12 studies	46% ± 19%	Explore
GABAergic neuron	11 studies	48% ± 25%	Explore
fibroblast	11 studies	36% ± 9%	Explore
B cell	10 studies	28% ± 12%	Explore
pericyte	9 studies	36% ± 12%	Explore
adipocyte	9 studies	49% ± 12%	Explore
mast cell	9 studies	32% ± 12%	Explore
smooth muscle cell	9 studies	29% ± 9%	Explore
myeloid cell	8 studies	35% ± 16%	Explore
epithelial cell	7 studies	37% ± 18%	Explore
dendritic cell	7 studies	40% ± 12%	Explore
endothelial cell of lymphatic vessel	7 studies	42% ± 13%	Explore
interneuron	6 studies	54% ± 21%	Explore
T cell	6 studies	35% ± 9%	Explore
natural killer cell	6 studies	30% ± 9%	Explore
neuron	5 studies	53% ± 18%	Explore
cardiac muscle cell	5 studies	30% ± 7%	Explore
monocyte	5 studies	49% ± 9%	Explore
type I pneumocyte	5 studies	41% ± 8%	Explore
type II pneumocyte	5 studies	36% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	23% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	4 studies	23% ± 10%	Explore
non-classical monocyte	4 studies	24% ± 5%	Explore
granule cell	4 studies	41% ± 10%	Explore
plasma cell	4 studies	37% ± 8%	Explore
CD4-positive, alpha-beta T cell	4 studies	29% ± 7%	Explore
CD8-positive, alpha-beta T cell	4 studies	28% ± 7%	Explore
mesothelial cell	4 studies	35% ± 10%	Explore
amacrine cell	4 studies	30% ± 8%	Explore
retina horizontal cell	4 studies	30% ± 13%	Explore
retinal cone cell	4 studies	29% ± 8%	Explore
retinal ganglion cell	4 studies	37% ± 19%	Explore
retinal rod cell	4 studies	26% ± 5%	Explore
ciliated cell	4 studies	30% ± 11%	Explore
club cell	4 studies	37% ± 8%	Explore
regulatory T cell	4 studies	29% ± 10%	Explore
classical monocyte	3 studies	22% ± 3%	Explore
GABAergic interneuron	3 studies	46% ± 4%	Explore
progenitor cell	3 studies	32% ± 1%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	28% ± 8%	Explore
vein endothelial cell	3 studies	40% ± 20%	Explore
GABAergic amacrine cell	3 studies	30% ± 9%	Explore
Mueller cell	3 studies	31% ± 10%	Explore
ON-bipolar cell	3 studies	26% ± 7%	Explore
glycinergic amacrine cell	3 studies	29% ± 10%	Explore
endothelial cell of vascular tree	3 studies	46% ± 19%	Explore
hepatocyte	3 studies	57% ± 18%	Explore
retinal pigment epithelial cell	3 studies	41% ± 19%	Explore
ependymal cell	3 studies	40% ± 23%	Explore
alveolar macrophage	3 studies	54% ± 11%	Explore
capillary endothelial cell	3 studies	36% ± 4%	Explore
respiratory goblet cell	3 studies	42% ± 13%	Explore
lymphocyte	3 studies	44% ± 14%	Explore
basal cell	3 studies	47% ± 19%	Explore
transit amplifying cell	3 studies	41% ± 32%	Explore
naive B cell	3 studies	17% ± 1%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	20% ± 3%	Explore
mucus secreting cell	3 studies	36% ± 7%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	16 studies	48% ± 20%	Explore
lung	6 studies	30% ± 11%	Explore
eye	5 studies	35% ± 16%	Explore
heart	4 studies	32% ± 4%	Explore
peripheral blood	3 studies	20% ± 1%	Explore
liver	3 studies	36% ± 18%	Explore
adipose	3 studies	47% ± 16%	Explore
kidney	3 studies	35% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1069.51	1445 / 1445	100%	8.64	183 / 183
lung	100%	1281.82	578 / 578	100%	7.85	1155 / 1155
uterus	100%	933.45	170 / 170	100%	8.19	459 / 459
stomach	100%	784.91	359 / 359	100%	8.43	285 / 286
breast	100%	1272.03	459 / 459	100%	9.09	1114 / 1118
prostate	100%	990.12	245 / 245	100%	6.88	500 / 502
ovary	100%	785.62	180 / 180	100%	6.56	428 / 430
thymus	100%	1147.50	653 / 653	100%	7.88	602 / 605
intestine	100%	1069.79	966 / 966	99%	8.55	524 / 527
bladder	100%	1017.86	21 / 21	99%	7.75	501 / 504
brain	99%	661.99	2612 / 2642	100%	6.75	705 / 705
pancreas	100%	560.58	327 / 328	99%	7.23	176 / 178
skin	100%	1496.35	1809 / 1809	97%	6.82	459 / 472
kidney	100%	1349.49	89 / 89	97%	5.49	872 / 901
adrenal gland	100%	931.83	258 / 258	93%	4.88	215 / 230
liver	99%	471.50	224 / 226	91%	3.80	368 / 406
adipose	100%	1353.66	1204 / 1204	0%	0	0 / 0
blood vessel	100%	1013.53	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	11.04	29 / 29
muscle	100%	898.71	803 / 803	0%	0	0 / 0
spleen	100%	1272.94	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	8.87	45 / 45
ureter	0%	0	0 / 0	100%	4.57	1 / 1
peripheral blood	99%	1348.84	922 / 929	0%	0	0 / 0
heart	96%	639.12	828 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	95%	5.72	76 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0050882	Biological process	voluntary musculoskeletal movement
GO_0048280	Biological process	vesicle fusion with Golgi apparatus
GO_0016189	Biological process	synaptic vesicle to endosome fusion
GO_0016236	Biological process	macroautophagy
GO_0006886	Biological process	intracellular protein transport
GO_0032456	Biological process	endocytic recycling
GO_0042147	Biological process	retrograde transport, endosome to Golgi
GO_0006891	Biological process	intra-Golgi vesicle-mediated transport
GO_0006896	Biological process	Golgi to vacuole transport
GO_0006914	Biological process	autophagy
GO_0006888	Biological process	endoplasmic reticulum to Golgi vesicle-mediated transport
GO_0031902	Cellular component	late endosome membrane
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0030136	Cellular component	clathrin-coated vesicle
GO_0005794	Cellular component	Golgi apparatus
GO_0043025	Cellular component	neuronal cell body
GO_0098686	Cellular component	hippocampal mossy fiber to CA3 synapse
GO_0032588	Cellular component	trans-Golgi network membrane
GO_0000139	Cellular component	Golgi membrane
GO_0005829	Cellular component	cytosol
GO_0008021	Cellular component	synaptic vesicle
GO_0005776	Cellular component	autophagosome
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0012507	Cellular component	ER to Golgi transport vesicle membrane
GO_0005768	Cellular component	endosome
GO_0044306	Cellular component	neuron projection terminus
GO_0031201	Cellular component	SNARE complex
GO_0000149	Molecular function	SNARE binding
GO_0005484	Molecular function	SNAP receptor activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	VTI1A
Protein name	Vesicle transport through interaction with t-SNAREs 1A Vesicle transport through interaction with t-SNAREs homolog 1A (Vesicle transport v-SNARE protein Vti1-like 2) (Vti1-rp2)
Synonyms
Description	FUNCTION: V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be involved in increased cytokine secretion associated with cellular senescence. .
Accessions	Q96AJ9 ENST00000705995.1 A0A994J5N6 ENST00000432306.5 [Q96AJ9-1] ENST00000393077.3 [Q96AJ9-2]

VTI1A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review