C1QL3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of C1QL3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of C1QL3 at tissue level.

III. Associated gene sets

GO_0050807Biological processregulation of synapse organization
GO_0099645Biological processneurotransmitter receptor localization to postsynaptic specialization membrane
GO_0097107Biological processpostsynaptic density assembly
GO_0043083Cellular componentsynaptic cleft
GO_0098978Cellular componentglutamatergic synapse
GO_0005581Cellular componentcollagen trimer
GO_0098686Cellular componenthippocampal mossy fiber to CA3 synapse
GO_0042802Molecular functionidentical protein binding

IV. Literature review

[source]
Gene nameC1QL3
Protein nameAlternative protein C1QL3
Adiponectin J (Complement component 1, q subcomponent-like 3)
Complement C1q-like protein 3 (C1q and tumor necrosis factor-related protein 13) (C1q/TNF-related protein 13)
SynonymshCG_23996
CTRP13
ADIJ
DescriptionFUNCTION: May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, reduces the expression of gluconeogenic enzymes G6PC1 and PCK1 and hence decreases de novo glucose production (By similarity). .

AccessionsL8EC65
Q5VWW1
ENST00000298943.4 [Q5VWW1-1]
A0A3B0J0F3