SLC16A7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0150104Biological processtransport across blood-brain barrier
GO_1901475Biological processpyruvate transmembrane transport
GO_0035879Biological processplasma membrane lactate transport
GO_0035873Biological processlactate transmembrane transport
GO_0098978Cellular componentglutamatergic synapse
GO_0098839Cellular componentpostsynaptic density membrane
GO_0098685Cellular componentSchaffer collateral - CA1 synapse
GO_0005886Cellular componentplasma membrane
GO_0005654Cellular componentnucleoplasm
GO_0098686Cellular componenthippocampal mossy fiber to CA3 synapse
GO_0005829Cellular componentcytosol
GO_0098688Cellular componentparallel fiber to Purkinje cell synapse
GO_0016323Cellular componentbasolateral plasma membrane
GO_0050833Molecular functionpyruvate transmembrane transporter activity
GO_0015129Molecular functionlactate transmembrane transporter activity
GO_0015293Molecular functionsymporter activity
GO_0042802Molecular functionidentical protein binding
GO_0005477Molecular functionpyruvate secondary active transmembrane transporter activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSLC16A7
Protein nameMonocarboxylate transporter 2 (Solute carrier family 16 member 7)
Monocarboxylate transporter 2 (MCT 2) (Solute carrier family 16 member 7)
Solute carrier family 16 member 7
SynonymsMCT2
DescriptionFUNCTION: Proton-coupled monocarboxylate symporter. Catalyzes the rapid transport across the plasma membrane of monocarboxylates such as L-lactate, pyruvate and ketone bodies, acetoacetate, beta-hydroxybutyrate and acetate . Dimerization is functionally required and both subunits work cooperatively in transporting substrate . .

AccessionsENST00000549928.5
F8VQS4
F8VYZ2
O60669
ENST00000548444.1
F8VVU7
ENST00000550062.5
F8VXG4
ENST00000552432.5
F8W0N3
F8W0U4
ENST00000552024.5
ENST00000546459.5
F8W1M4
ENST00000549033.5
ENST00000551877.5
ENST00000549305.1
ENST00000547379.6
ENST00000261187.8
ENST00000549465.5
ENST00000548610.5
F8VS95