Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 11 studies | 35% ± 17% | |
oligodendrocyte precursor cell | 8 studies | 36% ± 16% | |
microglial cell | 7 studies | 20% ± 5% | |
oligodendrocyte | 7 studies | 26% ± 8% | |
adipocyte | 6 studies | 21% ± 5% | |
GABAergic neuron | 6 studies | 42% ± 20% | |
glutamatergic neuron | 5 studies | 42% ± 22% | |
macrophage | 5 studies | 22% ± 3% | |
type I pneumocyte | 5 studies | 28% ± 7% | |
epithelial cell | 4 studies | 37% ± 8% | |
endothelial cell | 4 studies | 24% ± 6% | |
interneuron | 4 studies | 43% ± 21% | |
ciliated cell | 3 studies | 21% ± 7% | |
type II pneumocyte | 3 studies | 21% ± 4% | |
transit amplifying cell | 3 studies | 22% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 1051.35 | 2640 / 2642 | 100% | 21.02 | 703 / 705 |
prostate | 100% | 977.84 | 245 / 245 | 99% | 10.96 | 498 / 502 |
kidney | 100% | 487.64 | 89 / 89 | 98% | 9.18 | 883 / 901 |
thymus | 100% | 537.20 | 653 / 653 | 98% | 6.40 | 590 / 605 |
adrenal gland | 100% | 4695.24 | 258 / 258 | 96% | 14.56 | 221 / 230 |
breast | 100% | 653.43 | 459 / 459 | 94% | 5.42 | 1046 / 1118 |
liver | 100% | 1250.62 | 226 / 226 | 93% | 11.70 | 378 / 406 |
pancreas | 100% | 2412.17 | 328 / 328 | 92% | 11.07 | 163 / 178 |
intestine | 100% | 769.93 | 966 / 966 | 85% | 7.13 | 447 / 527 |
esophagus | 99% | 417.01 | 1427 / 1445 | 85% | 6.09 | 156 / 183 |
ovary | 100% | 965.54 | 180 / 180 | 84% | 3.95 | 361 / 430 |
lung | 99% | 520.74 | 572 / 578 | 85% | 4.51 | 977 / 1155 |
skin | 96% | 318.54 | 1729 / 1809 | 87% | 5.48 | 411 / 472 |
bladder | 100% | 861.14 | 21 / 21 | 81% | 5.17 | 409 / 504 |
stomach | 99% | 390.69 | 354 / 359 | 82% | 6.07 | 235 / 286 |
uterus | 100% | 605.05 | 170 / 170 | 81% | 6.61 | 370 / 459 |
adipose | 100% | 638.44 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 642.33 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.99 | 1 / 1 |
muscle | 99% | 672.68 | 797 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 419.13 | 1321 / 1335 | 0% | 0 | 0 / 0 |
heart | 92% | 369.34 | 791 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 85% | 5.43 | 68 / 80 |
tonsil | 0% | 0 | 0 / 0 | 80% | 4.20 | 36 / 45 |
lymph node | 0% | 0 | 0 / 0 | 79% | 3.54 | 23 / 29 |
peripheral blood | 43% | 115.72 | 400 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_1901381 | Biological process | positive regulation of potassium ion transmembrane transport |
GO_1902261 | Biological process | positive regulation of delayed rectifier potassium channel activity |
GO_0050804 | Biological process | modulation of chemical synaptic transmission |
GO_0006811 | Biological process | monoatomic ion transport |
GO_0008150 | Biological process | biological_process |
GO_0060306 | Biological process | regulation of membrane repolarization |
GO_0010738 | Biological process | regulation of protein kinase A signaling |
GO_0071320 | Biological process | cellular response to cAMP |
GO_0035556 | Biological process | intracellular signal transduction |
GO_0008104 | Biological process | protein localization |
GO_0001508 | Biological process | action potential |
GO_0016324 | Cellular component | apical plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0032991 | Cellular component | protein-containing complex |
GO_0098686 | Cellular component | hippocampal mossy fiber to CA3 synapse |
GO_0005829 | Cellular component | cytosol |
GO_0016328 | Cellular component | lateral plasma membrane |
GO_0005634 | Cellular component | nucleus |
GO_0034237 | Molecular function | protein kinase A regulatory subunit binding |
GO_0019901 | Molecular function | protein kinase binding |
GO_0000166 | Molecular function | nucleotide binding |
GO_0051018 | Molecular function | protein kinase A binding |
GO_0005515 | Molecular function | protein binding |
Gene name | AKAP7 |
Protein name | A-kinase anchor protein 7 isoform gamma (AKAP-7 isoform gamma) (A-kinase anchor protein 18 kDa) (AKAP 18) (Protein kinase A-anchoring protein 7 isoform gamma) (PRKA7 isoform gamma) A kinase (PRKA) anchor protein 7 A kinase (PRKA) anchor protein 7 (A-kinase anchor protein 7 isoform alpha) (cDNA, FLJ92081, Homo sapiens A kinase (PRKA) anchor protein 7 (AKAP7), transcriptvariant alpha, mRNA) A-kinase anchoring protein 7 A-kinase anchor protein 7 isoforms alpha and beta (AKAP-7 isoforms alpha and beta) (A-kinase anchor protein 18 kDa) (AKAP 18) (Protein kinase A-anchoring protein 7 isoforms alpha/beta) (PRKA7 isoforms alpha/beta) |
Synonyms | hCG_20012 AKAP15 AKAP18 |
Description | FUNCTION: Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium. . FUNCTION: Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium. . |
Accessions | Q6P4D3 A0A9L9PYJ6 ENST00000537868.5 ENST00000683794.1 ENST00000263050.3 ENST00000474850.2 [O43687-1] ENST00000706999.1 ENST00000431975.7 [Q9P0M2-1] A0A804HI88 F5GXD1 ENST00000342266.4 [O43687-2] Q2TAJ5 ENST00000541650.5 Q9P0M2 O43687 F5H4P9 J3KN37 |