I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 37% ± 20% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 37% ± 20% |
Insufficient scRNA-seq data for expression of SYT12 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 96% | 3261.62 | 2527 / 2642 | 79% | 5.01 | 557 / 705 |
| liver | 99% | 1959.19 | 223 / 226 | 72% | 8.26 | 294 / 406 |
| breast | 49% | 482.97 | 223 / 459 | 84% | 13.65 | 936 / 1118 |
| adrenal gland | 81% | 1176.65 | 210 / 258 | 11% | 0.58 | 25 / 230 |
| prostate | 64% | 340.07 | 158 / 245 | 25% | 0.76 | 123 / 502 |
| blood vessel | 80% | 965.88 | 1069 / 1335 | 0% | 0 | 0 / 0 |
| thymus | 1% | 54.61 | 5 / 653 | 62% | 24.20 | 376 / 605 |
| pancreas | 2% | 10.34 | 8 / 328 | 60% | 4.44 | 106 / 178 |
| ovary | 3% | 9.69 | 5 / 180 | 50% | 3.10 | 216 / 430 |
| lung | 1% | 3.04 | 7 / 578 | 40% | 5.42 | 459 / 1155 |
| kidney | 8% | 20.47 | 7 / 89 | 32% | 2.21 | 291 / 901 |
| uterus | 1% | 12.16 | 2 / 170 | 32% | 3.37 | 148 / 459 |
| esophagus | 2% | 6.66 | 34 / 1445 | 28% | 1.76 | 52 / 183 |
| skin | 22% | 72.29 | 397 / 1809 | 7% | 0.34 | 33 / 472 |
| bladder | 0% | 0 | 0 / 21 | 23% | 2.19 | 117 / 504 |
| tonsil | 0% | 0 | 0 / 0 | 13% | 0.42 | 6 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 0.32 | 3 / 29 |
| intestine | 1% | 4.61 | 13 / 966 | 7% | 0.40 | 37 / 527 |
| heart | 8% | 31.53 | 69 / 861 | 0% | 0 | 0 / 0 |
| stomach | 3% | 6.36 | 9 / 359 | 5% | 0.25 | 15 / 286 |
| adipose | 4% | 14.03 | 51 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 2% | 5.08 | 14 / 929 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0.29 | 1 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0017156 | Biological process | calcium-ion regulated exocytosis |
| GO_0060291 | Biological process | long-term synaptic potentiation |
| GO_0099171 | Biological process | presynaptic modulation of chemical synaptic transmission |
| GO_0048792 | Biological process | spontaneous exocytosis of neurotransmitter |
| GO_0070382 | Cellular component | exocytic vesicle |
| GO_0030672 | Cellular component | synaptic vesicle membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0098686 | Cellular component | hippocampal mossy fiber to CA3 synapse |
| GO_0030276 | Molecular function | clathrin binding |
| GO_0000149 | Molecular function | SNARE binding |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0001786 | Molecular function | phosphatidylserine binding |
| GO_0005544 | Molecular function | calcium-dependent phospholipid binding |
| Gene name | SYT12 |
| Protein name | Synaptotagmin-12 (Synaptotagmin XII) (SytXII) Synaptotagmin 12 |
| Synonyms | |
| Description | FUNCTION: Synaptic vesicle phosphoprotein that enhances spontaneous neurotransmitter release but does not effect induced neurotransmitter release (By similarity). Unlike other synaptotagmins, it does not bind Ca(2+) or phospholipids (By similarity). Essential for mossy-fiber long-term potentiation in the hippocampus (By similarity). . |
| Accessions | E9PNM5 ENST00000393946.6 ENST00000533427.1 ENST00000525457.5 ENST00000527043.6 Q8IV01 |
