SLC6A9 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC6A9 at tissue level.

III. Associated gene sets

GO_0070455Biological processpositive regulation of heme biosynthetic process
GO_0060092Biological processregulation of synaptic transmission, glycinergic
GO_0150104Biological processtransport across blood-brain barrier
GO_1903804Biological processglycine import across plasma membrane
GO_0060012Biological processsynaptic transmission, glycinergic
GO_0015816Biological processglycine transport
GO_0006836Biological processneurotransmitter transport
GO_1904782Biological processnegative regulation of NMDA glutamate receptor activity
GO_0046985Biological processpositive regulation of hemoglobin biosynthetic process
GO_0035725Biological processsodium ion transmembrane transport
GO_0016324Cellular componentapical plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0030672Cellular componentsynaptic vesicle membrane
GO_0098686Cellular componenthippocampal mossy fiber to CA3 synapse
GO_0009925Cellular componentbasal plasma membrane
GO_0042734Cellular componentpresynaptic membrane
GO_0031045Cellular componentdense core granule
GO_0014069Cellular componentpostsynaptic density
GO_0016328Cellular componentlateral plasma membrane
GO_0045211Cellular componentpostsynaptic membrane
GO_0005768Cellular componentendosome
GO_0098688Cellular componentparallel fiber to Purkinje cell synapse
GO_0016323Cellular componentbasolateral plasma membrane
GO_0015187Molecular functionglycine transmembrane transporter activity
GO_0015375Molecular functionglycine:sodium symporter activity

IV. Literature review

[source]
Gene nameSLC6A9
Protein nameSodium- and chloride-dependent glycine transporter 1 (Solute carrier family 6 member 9)
Transporter
Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9)
Synonyms
DescriptionFUNCTION: Sodium- and chloride-dependent glycine transporter . Essential for regulating glycine concentrations at inhibitory glycinergic synapses. .; FUNCTION: [Isoform GlyT-1B]: Sodium- and chloride-dependent glycine transporter. .; FUNCTION: [Isoform GlyT-1C]: Sodium- and chloride-dependent glycine transporter. .

AccessionsENST00000475075.6
ENST00000528803.1
ENST00000372306.7
ENST00000673836.1 [P48067-2]
ENST00000372307.7
ENST00000372310.8 [P48067-2]
ENST00000360584.6 [P48067-1]
B7Z589
ENST00000466926.1
P48067
E9PLM5
ENST00000357730.6 [P48067-3]
B7Z3A9
E9PJ65
J3KPA5