ACTG1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	50 studies	70% ± 24%	Explore
B cell	49 studies	70% ± 22%	Explore
macrophage	48 studies	73% ± 24%	Explore
natural killer cell	48 studies	81% ± 19%	Explore
fibroblast	47 studies	73% ± 27%	Explore
T cell	44 studies	73% ± 26%	Explore
CD8-positive, alpha-beta T cell	42 studies	78% ± 22%	Explore
pericyte	39 studies	76% ± 25%	Explore
CD4-positive, alpha-beta T cell	36 studies	78% ± 23%	Explore
smooth muscle cell	33 studies	75% ± 26%	Explore
conventional dendritic cell	33 studies	91% ± 15%	Explore
plasmacytoid dendritic cell	33 studies	83% ± 17%	Explore
dendritic cell	31 studies	84% ± 20%	Explore
classical monocyte	29 studies	85% ± 15%	Explore
regulatory T cell	29 studies	89% ± 12%	Explore
monocyte	28 studies	74% ± 26%	Explore
non-classical monocyte	27 studies	88% ± 16%	Explore
endothelial cell of lymphatic vessel	26 studies	75% ± 25%	Explore
epithelial cell	26 studies	85% ± 20%	Explore
plasma cell	25 studies	67% ± 19%	Explore
mature NK T cell	25 studies	78% ± 18%	Explore
mast cell	23 studies	61% ± 21%	Explore
basal cell	23 studies	83% ± 21%	Explore
gamma-delta T cell	22 studies	81% ± 20%	Explore
memory B cell	21 studies	82% ± 15%	Explore
connective tissue cell	21 studies	79% ± 24%	Explore
naive B cell	19 studies	72% ± 13%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	19 studies	77% ± 21%	Explore
ciliated cell	18 studies	77% ± 18%	Explore
capillary endothelial cell	17 studies	72% ± 17%	Explore
myeloid cell	17 studies	69% ± 31%	Explore
CD16-negative, CD56-bright natural killer cell, human	16 studies	80% ± 22%	Explore
mucosal invariant T cell	16 studies	83% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	16 studies	85% ± 16%	Explore
neutrophil	16 studies	68% ± 19%	Explore
endothelial cell of artery	16 studies	78% ± 14%	Explore
astrocyte	16 studies	50% ± 23%	Explore
myofibroblast cell	16 studies	87% ± 20%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	15 studies	83% ± 20%	Explore
vein endothelial cell	15 studies	76% ± 20%	Explore
endothelial cell of vascular tree	15 studies	76% ± 27%	Explore
innate lymphoid cell	14 studies	80% ± 15%	Explore
CD4-positive, alpha-beta memory T cell	13 studies	82% ± 16%	Explore
CD8-positive, alpha-beta memory T cell	13 studies	84% ± 16%	Explore
microglial cell	13 studies	54% ± 31%	Explore
effector memory CD8-positive, alpha-beta T cell	12 studies	72% ± 23%	Explore
plasmablast	12 studies	82% ± 13%	Explore
secretory cell	12 studies	91% ± 10%	Explore
leukocyte	12 studies	75% ± 20%	Explore
erythrocyte	12 studies	51% ± 20%	Explore
mesothelial cell	12 studies	78% ± 28%	Explore
type I pneumocyte	11 studies	80% ± 22%	Explore
platelet	11 studies	75% ± 21%	Explore
club cell	11 studies	76% ± 28%	Explore
progenitor cell	11 studies	86% ± 22%	Explore
goblet cell	11 studies	81% ± 19%	Explore
type II pneumocyte	10 studies	72% ± 25%	Explore
T follicular helper cell	10 studies	89% ± 9%	Explore
oligodendrocyte precursor cell	10 studies	43% ± 27%	Explore
abnormal cell	10 studies	82% ± 23%	Explore
effector CD8-positive, alpha-beta T cell	9 studies	91% ± 10%	Explore
oligodendrocyte	9 studies	38% ± 12%	Explore
neuron	9 studies	75% ± 22%	Explore
IgG plasma cell	9 studies	48% ± 13%	Explore
respiratory goblet cell	8 studies	77% ± 26%	Explore
mononuclear phagocyte	8 studies	68% ± 27%	Explore
enterocyte	8 studies	77% ± 22%	Explore
IgA plasma cell	8 studies	53% ± 16%	Explore
hematopoietic stem cell	8 studies	96% ± 5%	Explore
brush cell	8 studies	73% ± 24%	Explore
alveolar macrophage	7 studies	77% ± 22%	Explore
ionocyte	7 studies	90% ± 9%	Explore
effector CD4-positive, alpha-beta T cell	7 studies	83% ± 25%	Explore
GABAergic neuron	7 studies	39% ± 21%	Explore
glutamatergic neuron	7 studies	44% ± 20%	Explore
epithelial cell of proximal tubule	7 studies	66% ± 20%	Explore
enteroendocrine cell	7 studies	88% ± 14%	Explore
transit amplifying cell	7 studies	69% ± 29%	Explore
amacrine cell	7 studies	53% ± 27%	Explore
retinal ganglion cell	7 studies	70% ± 31%	Explore
glial cell	7 studies	63% ± 27%	Explore
precursor B cell	7 studies	84% ± 25%	Explore
CD4-positive helper T cell	6 studies	77% ± 9%	Explore
CD4-positive, alpha-beta cytotoxic T cell	6 studies	80% ± 21%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	6 studies	72% ± 27%	Explore
hematopoietic precursor cell	6 studies	78% ± 28%	Explore
kidney loop of Henle epithelial cell	6 studies	74% ± 16%	Explore
renal alpha-intercalated cell	6 studies	95% ± 4%	Explore
megakaryocyte	6 studies	78% ± 28%	Explore
erythroblast	6 studies	53% ± 25%	Explore
interneuron	6 studies	53% ± 25%	Explore
retinal cone cell	6 studies	66% ± 27%	Explore
retinal rod cell	6 studies	57% ± 23%	Explore
lymphocyte	6 studies	70% ± 34%	Explore
immature B cell	6 studies	91% ± 8%	Explore
Mueller cell	6 studies	66% ± 28%	Explore
intermediate monocyte	6 studies	85% ± 17%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	88% ± 8%	Explore
granulocyte	6 studies	79% ± 11%	Explore
melanocyte	6 studies	84% ± 20%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	85% ± 9%	Explore
duct epithelial cell	5 studies	76% ± 29%	Explore
exhausted T cell	5 studies	92% ± 10%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	92% ± 8%	Explore
intestinal crypt stem cell	5 studies	82% ± 26%	Explore
OFF-bipolar cell	5 studies	61% ± 26%	Explore
ON-bipolar cell	5 studies	60% ± 26%	Explore
neuroendocrine cell	5 studies	92% ± 10%	Explore
Schwann cell	5 studies	64% ± 35%	Explore
T-helper 17 cell	5 studies	92% ± 7%	Explore
group 3 innate lymphoid cell	5 studies	94% ± 4%	Explore
retina horizontal cell	5 studies	60% ± 20%	Explore
mucus secreting cell	5 studies	64% ± 24%	Explore
cardiac muscle cell	5 studies	44% ± 10%	Explore
inflammatory macrophage	5 studies	69% ± 18%	Explore
double negative thymocyte	5 studies	94% ± 5%	Explore
hepatocyte	5 studies	49% ± 20%	Explore
keratinocyte	5 studies	81% ± 27%	Explore
deuterosomal cell	4 studies	72% ± 12%	Explore
precursor cell	4 studies	87% ± 20%	Explore
squamous epithelial cell	4 studies	87% ± 9%	Explore
pancreatic A cell	4 studies	83% ± 12%	Explore
type B pancreatic cell	4 studies	84% ± 14%	Explore
monocyte-derived dendritic cell	4 studies	87% ± 13%	Explore
endothelial cell of sinusoid	4 studies	38% ± 24%	Explore
glomerular endothelial cell	4 studies	63% ± 13%	Explore
kidney connecting tubule epithelial cell	4 studies	93% ± 6%	Explore
podocyte	4 studies	97% ± 3%	Explore
retinal bipolar neuron	4 studies	58% ± 26%	Explore
granule cell	4 studies	27% ± 13%	Explore
GABAergic amacrine cell	4 studies	57% ± 17%	Explore
glycinergic amacrine cell	4 studies	51% ± 23%	Explore
renal principal cell	4 studies	76% ± 33%	Explore
pro-B cell	4 studies	95% ± 3%	Explore
chondrocyte	4 studies	68% ± 19%	Explore
retinal pigment epithelial cell	4 studies	76% ± 18%	Explore
adventitial cell	4 studies	86% ± 16%	Explore
acinar cell	4 studies	68% ± 32%	Explore
germinal center B cell	4 studies	97% ± 3%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	94% ± 6%	Explore
luminal cell of prostate epithelium	4 studies	75% ± 29%	Explore
T-helper 1 cell	4 studies	95% ± 3%	Explore
Langerhans cell	3 studies	93% ± 5%	Explore
hillock cell	3 studies	75% ± 29%	Explore
pancreatic D cell	3 studies	87% ± 9%	Explore
cholangiocyte	3 studies	25% ± 8%	Explore
renal beta-intercalated cell	3 studies	97% ± 3%	Explore
neural crest cell	3 studies	99% ± 1%	Explore
paneth cell	3 studies	77% ± 16%	Explore
thymocyte	3 studies	84% ± 19%	Explore
extravillous trophoblast	3 studies	99% ± 1%	Explore
placental villous trophoblast	3 studies	92% ± 8%	Explore
serous secreting cell	3 studies	46% ± 26%	Explore
tissue-resident macrophage	3 studies	71% ± 26%	Explore
follicular B cell	3 studies	70% ± 9%	Explore
intraepithelial lymphocyte	3 studies	95% ± 3%	Explore
rod bipolar cell	3 studies	62% ± 21%	Explore
adipocyte	3 studies	23% ± 0%	Explore
myoepithelial cell	3 studies	100% ± 0%	Explore
IgM plasma cell	3 studies	54% ± 18%	Explore
muscle cell	3 studies	66% ± 15%	Explore
pancreatic ductal cell	3 studies	94% ± 4%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	99% ± 0%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	91% ± 1%	Explore
double-positive, alpha-beta thymocyte	3 studies	96% ± 3%	Explore
progenitor cell of mammary luminal epithelium	3 studies	98% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	22 studies	81% ± 15%	Explore
lung	20 studies	76% ± 19%	Explore
brain	15 studies	44% ± 16%	Explore
intestine	14 studies	71% ± 24%	Explore
eye	11 studies	63% ± 22%	Explore
liver	9 studies	48% ± 28%	Explore
kidney	9 studies	76% ± 18%	Explore
lymph node	7 studies	86% ± 11%	Explore
heart	7 studies	36% ± 16%	Explore
bone marrow	6 studies	73% ± 20%	Explore
uterus	6 studies	75% ± 30%	Explore
pancreas	5 studies	75% ± 23%	Explore
esophagus	5 studies	58% ± 30%	Explore
prostate	5 studies	70% ± 31%	Explore
placenta	4 studies	81% ± 20%	Explore
adipose	4 studies	55% ± 25%	Explore
skin	4 studies	81% ± 12%	Explore
breast	4 studies	91% ± 6%	Explore
ovary	3 studies	65% ± 26%	Explore
adrenal gland	3 studies	82% ± 12%	Explore
stomach	3 studies	57% ± 26%	Explore
thymus	3 studies	86% ± 19%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	183680.50	180 / 180	100%	3770.43	430 / 430
skin	100%	181909.52	1809 / 1809	100%	5563.33	472 / 472
stomach	100%	108796.78	359 / 359	100%	4495.35	286 / 286
esophagus	100%	127385.70	1444 / 1445	100%	4780.04	183 / 183
thymus	100%	106326.67	653 / 653	100%	4682.70	604 / 605
lung	100%	149454.27	577 / 578	100%	4125.71	1155 / 1155
intestine	100%	108362.76	966 / 966	100%	4855.59	526 / 527
bladder	100%	104234.62	21 / 21	100%	4721.65	503 / 504
uterus	100%	142885.64	170 / 170	100%	4587.01	458 / 459
breast	100%	119194.42	459 / 459	100%	4677.46	1115 / 1118
prostate	100%	84283.30	245 / 245	99%	3258.73	498 / 502
kidney	100%	96332.09	89 / 89	98%	2397.50	886 / 901
pancreas	97%	109466.36	319 / 328	99%	3827.57	177 / 178
brain	96%	59560.41	2549 / 2642	100%	3109.25	705 / 705
adrenal gland	100%	93274.85	258 / 258	92%	1888.17	211 / 230
liver	85%	45071.26	191 / 226	88%	1671.53	358 / 406
adipose	100%	136580.44	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	5945.82	80 / 80
lymph node	0%	0	0 / 0	100%	4982.09	29 / 29
spleen	100%	110600.11	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	4146.61	45 / 45
ureter	0%	0	0 / 0	100%	2616.67	1 / 1
blood vessel	100%	150306.61	1334 / 1335	0%	0	0 / 0
peripheral blood	99%	131199.96	917 / 929	0%	0	0 / 0
heart	84%	42078.09	723 / 861	0%	0	0 / 0
muscle	49%	16442.94	393 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0048870	Biological process	cell motility
GO_0001525	Biological process	angiogenesis
GO_1900242	Biological process	regulation of synaptic vesicle endocytosis
GO_0070527	Biological process	platelet aggregation
GO_0010628	Biological process	positive regulation of gene expression
GO_0098974	Biological process	postsynaptic actin cytoskeleton organization
GO_1902396	Biological process	protein localization to bicellular tight junction
GO_0007409	Biological process	axonogenesis
GO_0030335	Biological process	positive regulation of cell migration
GO_0051492	Biological process	regulation of stress fiber assembly
GO_0051893	Biological process	regulation of focal adhesion assembly
GO_0035633	Biological process	maintenance of blood-brain barrier
GO_0090303	Biological process	positive regulation of wound healing
GO_0001738	Biological process	morphogenesis of a polarized epithelium
GO_0045214	Biological process	sarcomere organization
GO_0120192	Biological process	tight junction assembly
GO_0150111	Biological process	regulation of transepithelial transport
GO_0071346	Biological process	cellular response to type II interferon
GO_0005615	Cellular component	extracellular space
GO_0120220	Cellular component	basal body patch
GO_0005856	Cellular component	cytoskeleton
GO_0031941	Cellular component	filamentous actin
GO_0098685	Cellular component	Schaffer collateral - CA1 synapse
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0030016	Cellular component	myofibril
GO_0070062	Cellular component	extracellular exosome
GO_0005884	Cellular component	actin filament
GO_0005925	Cellular component	focal adhesion
GO_0005911	Cellular component	cell-cell junction
GO_0035267	Cellular component	NuA4 histone acetyltransferase complex
GO_0072562	Cellular component	blood microparticle
GO_0097433	Cellular component	dense body
GO_0043296	Cellular component	apical junction complex
GO_0015629	Cellular component	actin cytoskeleton
GO_0044305	Cellular component	calyx of Held
GO_0005829	Cellular component	cytosol
GO_0045335	Cellular component	phagocytic vesicle
GO_0045202	Cellular component	synapse
GO_0005737	Cellular component	cytoplasm
GO_0030424	Cellular component	axon
GO_0005634	Cellular component	nucleus
GO_0005200	Molecular function	structural constituent of cytoskeleton
GO_0016787	Molecular function	hydrolase activity
GO_0019901	Molecular function	protein kinase binding
GO_0098973	Molecular function	structural constituent of postsynaptic actin cytoskeleton
GO_0042802	Molecular function	identical protein binding
GO_0031625	Molecular function	ubiquitin protein ligase binding
GO_0005524	Molecular function	ATP binding
GO_0005522	Molecular function	profilin binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	ACTG1
Protein name	ACTG1 protein Actin, cytoplasmic 2 Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed] Actin, cytoplasmic 2 (Gamma-actin) Actin gamma 1
Synonyms	ACTG
Description	FUNCTION: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. .
Accessions	ENST00000576544.6 ENST00000679480.1 A0A7P0TBL1 ENST00000707472.1 I3L4N8 ENST00000575659 ENST00000707479.1 ENST00000575994 I3L1U9 ENST00000707471.1 ENST00000571721 ENST00000571721.6 ENST00000707485.1 ENST00000681052.1 ENST00000680727.1 ENST00000679778.1 ENST00000681842.1 ENST00000707469.1 K7EM38 ENST00000680227.1 ENST00000707468.1 ENST00000644774.2 Q96FU6 ENST00000707487.1 ENST00000707466.1 ENST00000707474.1 ENST00000707473.1 ENST00000707489.1 A0A804GS07 ENST00000575994.6 ENST00000571691.6 ENST00000570382.2 ENST00000681092.1 ENST00000707490.1 ENST00000572105.7 J3KT65 ENST00000707470.1 ENST00000707467.1 ENST00000573283.7 ENST00000575659.6 ENST00000575842.5 ENST00000570382 ENST00000707482.1 P63261 ENST00000575087.5 Q6PJ43 I3L3I0 I3L3R2 ENST00000615544.5

ACTG1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review