inflammatory macrophage report

I. Related cell sub types

II. Gene markers

Gene
Number of
supported studies
Average coverage
Other major groups
(express this gene)
Other cell types
(express this gene)
SLC11A1346% ± 12%011
FCN1345% ± 5%111
CSF1R329% ± 11%112
MS4A4A327% ± 8%112
C1QB357% ± 25%113
CD163359% ± 10%114
IGSF6332% ± 17%115
CLEC7A341% ± 7%115
MS4A7335% ± 14%115
IL1R2330% ± 6%29
C5AR1327% ± 6%214
MPEG1336% ± 5%214
C1QA364% ± 23%216
MS4A6A362% ± 9%218
CYBB350% ± 5%219
CCL3355% ± 24%221
CD14349% ± 9%318
CXCL16336% ± 11%323
HMOX1437% ± 10%420
FCER1G566% ± 24%432
LST1457% ± 21%425
CPVL329% ± 2%418
CXCL3328% ± 14%418
KYNU342% ± 12%418
SPI1442% ± 17%430
TGFBI327% ± 6%420
TYROBP580% ± 14%440
FGL2343% ± 5%421
TNFAIP2330% ± 17%427
THBS1327% ± 12%431

III. Associated gene sets

GO_1900122Biological processpositive regulation of receptor binding
GO_0071492Biological processcellular response to UV-A

IV. Literature review

[source]
Cell type nameinflammatory macrophage
Synonymsclassically activated macrophage
DescriptionAn elicited macrophage that is recruited into the tissues in response to injury and infection as part of an inflammatory response, expresses high levels of pro-inflammatory cytokines, ROS and NO, and shows potent microbicidal activity.
ParentCL_0000235