Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 45 studies | 49% ± 19% | |
| non-classical monocyte | 20 studies | 34% ± 8% | |
| myeloid cell | 12 studies | 38% ± 8% | |
| monocyte | 11 studies | 27% ± 14% | |
| classical monocyte | 8 studies | 24% ± 11% | |
| alveolar macrophage | 7 studies | 45% ± 9% | |
| conventional dendritic cell | 7 studies | 24% ± 9% | |
| dendritic cell | 6 studies | 31% ± 14% | |
| mononuclear phagocyte | 5 studies | 37% ± 13% | |
| leukocyte | 4 studies | 25% ± 4% | |
| microglial cell | 4 studies | 34% ± 11% | |
| tissue-resident macrophage | 3 studies | 50% ± 2% | |
| inflammatory macrophage | 3 studies | 27% ± 8% |
Insufficient scRNA-seq data for expression of MS4A4A at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 98% | 2022.61 | 569 / 578 | 89% | 21.35 | 1031 / 1155 |
| breast | 91% | 1074.77 | 418 / 459 | 90% | 13.41 | 1003 / 1118 |
| bladder | 95% | 793.33 | 20 / 21 | 63% | 11.20 | 317 / 504 |
| adrenal gland | 94% | 1320.75 | 243 / 258 | 62% | 8.78 | 142 / 230 |
| intestine | 94% | 928.37 | 905 / 966 | 61% | 8.13 | 319 / 527 |
| stomach | 67% | 435.22 | 240 / 359 | 70% | 10.46 | 201 / 286 |
| kidney | 46% | 366.94 | 41 / 89 | 84% | 21.80 | 758 / 901 |
| thymus | 54% | 319.99 | 355 / 653 | 72% | 8.29 | 435 / 605 |
| esophagus | 65% | 564.77 | 935 / 1445 | 59% | 6.32 | 108 / 183 |
| ovary | 54% | 313.97 | 97 / 180 | 69% | 8.71 | 298 / 430 |
| uterus | 58% | 314.49 | 99 / 170 | 62% | 8.22 | 284 / 459 |
| prostate | 60% | 306.61 | 146 / 245 | 58% | 4.75 | 289 / 502 |
| pancreas | 28% | 113.55 | 93 / 328 | 85% | 19.99 | 151 / 178 |
| skin | 30% | 130.40 | 541 / 1809 | 83% | 14.72 | 390 / 472 |
| brain | 21% | 102.33 | 561 / 2642 | 82% | 20.78 | 580 / 705 |
| adipose | 99% | 2570.48 | 1190 / 1204 | 0% | 0 | 0 / 0 |
| liver | 34% | 198.87 | 76 / 226 | 64% | 7.21 | 258 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 27.84 | 28 / 29 |
| spleen | 96% | 2830.59 | 231 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 76% | 896.81 | 1011 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 71% | 9.10 | 32 / 45 |
| peripheral blood | 69% | 1237.75 | 645 / 929 | 0% | 0 | 0 / 0 |
| heart | 55% | 309.10 | 471 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 49% | 4.96 | 39 / 80 |
| muscle | 18% | 63.75 | 142 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0044853 | Cellular component | plasma membrane raft |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005515 | Molecular function | protein binding |
| Gene name | MS4A4A |
| Protein name | Epididymis secretory sperm binding protein (Membrane spanning 4-domains A4A) (Membrane-spanning 4-domains, subfamily A, member 4, isoform CRA_c) Membrane-spanning 4-domains subfamily A member 4A (CD20 antigen-like 1) (Four-span transmembrane protein 1) Membrane spanning 4-domains A4A |
| Synonyms | CD20L1 4SPAN1 hCG_40406 MS4A4 HDCME31P |
| Description | FUNCTION: May be involved in signal transduction as a component of a multimeric receptor complex. |
| Accessions | ENST00000680537.1 ENST00000681406.1 ENST00000679385.1 F8W866 ENST00000649552.2 Q96JQ5 ENST00000680935.1 A0A7P0TAE4 ENST00000679553.1 ENST00000527056.5 A0A384MDW1 ENST00000680757.1 A0A7P0Z4L9 H0YE49 ENST00000337908.5 [Q96JQ5-1] ENST00000680560.1 ENST00000343968.8 ENST00000680301.1 ENST00000681288.1 A0A7P0T9I4 ENST00000529950.2 A0A7P0Z422 ENST00000532114.6 [Q96JQ5-2] ENST00000679988.1 A0A7P0TA01 A0A7P0T8A0 A0A3B3ITV6 ENST00000681157.1 |