CXCL3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0071222Biological processcellular response to lipopolysaccharide
GO_0061844Biological processantimicrobial humoral immune response mediated by antimicrobial peptide
GO_0030593Biological processneutrophil chemotaxis
GO_0070098Biological processchemokine-mediated signaling pathway
GO_0006954Biological processinflammatory response
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0045236Molecular functionCXCR chemokine receptor binding
GO_0008009Molecular functionchemokine activity

IV. Literature review

[source]
Gene nameCXCL3
Protein nameC-X-C motif chemokine 3 (GRO-gamma(1-73)) (Growth-regulated protein gamma) (GRO-gamma) (Macrophage inflammatory protein 2-beta) (MIP2-beta) [Cleaved into: GRO-gamma(5-73)]
SynonymsSCYB3
GRO3
GROG
DescriptionFUNCTION: Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. .

AccessionsP19876
ENST00000296026.4