C1QB report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006958Biological processcomplement activation, classical pathway
GO_0006956Biological processcomplement activation
GO_0098883Biological processsynapse pruning
GO_0045087Biological processinnate immune response
GO_0072562Cellular componentblood microparticle
GO_0062167Cellular componentcomplement component C1q complex
GO_0005581Cellular componentcollagen trimer
GO_0045202Cellular componentsynapse
GO_0005576Cellular componentextracellular region
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0098794Cellular componentpostsynapse
GO_0005602Cellular componentcomplement component C1 complex
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameC1QB
Protein nameComplement C1q subcomponent subunit B
Adiponectin A (Complement component 1, q subcomponent, B chain, isoform CRA_a)
Complement C1q B chain
Complement subcomponent C1q chain B
SynonymsADIA
hCG_39967
DescriptionFUNCTION: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

AccessionsENST00000695757.1
ENST00000695755.1
ENST00000695760.1
ENST00000509305.6
D6RGJ1
A0A024RAB9
A0A8Q3WM25
ENST00000695756.1
A0A0A0MSV6
ENST00000695758.1
Q6LDZ7
ENST00000695759.1
ENST00000510260.5
ENST00000695762.1
A0A8Q3WLT6
P02746
ENST00000432749.6
ENST00000695763.1
A0A8Q3SI50
ENST00000695761.1
A0A8Q3SI33
ENST00000695754.1
D6R934
A0A8Q3WKR5
A0A8Q3SI72