complement activation

I. Literature review

[source]
Namecomplement activation
IDGO_0006956
collection_id

Biological process

Exact synonym

complement cascade, complement response

Related synonym

complement activity

Description

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

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Genes