CFHR5 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CFHR5 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CFHR5 at tissue level.

III. Associated gene sets

GO_0006957Biological processcomplement activation, alternative pathway
GO_0032091Biological processnegative regulation of protein binding
GO_0006956Biological processcomplement activation
GO_0051838Biological processcytolysis by host of symbiont cells
GO_0005615Cellular componentextracellular space
GO_0032991Cellular componentprotein-containing complex
GO_0005576Cellular componentextracellular region
GO_0046982Molecular functionprotein heterodimerization activity
GO_0001851Molecular functioncomplement component C3b binding
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCFHR5
Protein nameCFHR5 protein
Complement factor H related 5
Complement factor H-related protein 5 (FHR-5)
SynonymsCFHL5
FHR5
DescriptionFUNCTION: Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. .

AccessionsENST00000256785.5
ENST00000699466.1
Q9BXR6
ENST00000699468.1
A0A8V8TNA3
Q05CF5
ENST00000709541.1
A0A8V8TNF4