CFD report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006957Biological processcomplement activation, alternative pathway
GO_0006956Biological processcomplement activation
GO_0006508Biological processproteolysis
GO_0009617Biological processresponse to bacterium
GO_1904813Cellular componentficolin-1-rich granule lumen
GO_0070062Cellular componentextracellular exosome
GO_0031093Cellular componentplatelet alpha granule lumen
GO_0005576Cellular componentextracellular region
GO_0034774Cellular componentsecretory granule lumen
GO_0008236Molecular functionserine-type peptidase activity
GO_0004252Molecular functionserine-type endopeptidase activity

IV. Literature review

[source]
Gene nameCFD
Protein nameComplement factor D (EC 3.4.21.46) (Adipsin) (C3 convertase activator) (Properdin factor D)
SynonymsDF
PFD
DescriptionFUNCTION: Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.

FUNCTION: Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. .

FUNCTION: Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. .

FUNCTION: Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. .

FUNCTION: Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. .

AccessionsENST00000327726.11
ENST00000695942.1
K7ERG9
ENST00000695945.1
ENST00000695943.1
A0A8Q3WKV6
ENST00000695946.1
ENST00000592860.3
ENST00000617994.2
ENST00000695944.1
P00746
A0A8Q3WKW0
A0A8Q3WLE6
ENST00000632706.1