Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 40 studies | 54% ± 25% | |
macrophage | 39 studies | 38% ± 20% | |
classical monocyte | 27 studies | 60% ± 17% | |
non-classical monocyte | 27 studies | 72% ± 25% | |
monocyte | 22 studies | 51% ± 18% | |
conventional dendritic cell | 15 studies | 24% ± 9% | |
myeloid cell | 12 studies | 28% ± 11% | |
neutrophil | 10 studies | 43% ± 14% | |
dendritic cell | 10 studies | 33% ± 19% | |
connective tissue cell | 10 studies | 62% ± 30% | |
adipocyte | 9 studies | 46% ± 22% | |
pericyte | 8 studies | 39% ± 16% | |
alveolar macrophage | 6 studies | 50% ± 15% | |
mononuclear phagocyte | 6 studies | 43% ± 23% | |
epithelial cell | 6 studies | 32% ± 12% | |
smooth muscle cell | 6 studies | 23% ± 14% | |
adventitial cell | 5 studies | 73% ± 30% | |
intermediate monocyte | 5 studies | 69% ± 26% | |
endothelial cell | 4 studies | 31% ± 15% | |
secretory cell | 3 studies | 23% ± 5% | |
lymphocyte | 3 studies | 23% ± 4% | |
tissue-resident macrophage | 3 studies | 32% ± 11% | |
ciliated cell | 3 studies | 26% ± 6% | |
mast cell | 3 studies | 31% ± 16% | |
microglial cell | 3 studies | 20% ± 4% | |
T cell | 3 studies | 40% ± 16% | |
endothelial cell of lymphatic vessel | 3 studies | 66% ± 7% | |
basal cell | 3 studies | 36% ± 14% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 95% | 15322.30 | 550 / 578 | 90% | 58.13 | 1043 / 1155 |
bladder | 100% | 38417.76 | 21 / 21 | 81% | 56.83 | 406 / 504 |
breast | 99% | 44246.66 | 454 / 459 | 81% | 95.22 | 911 / 1118 |
thymus | 93% | 15630.50 | 605 / 653 | 83% | 30.41 | 501 / 605 |
prostate | 75% | 12108.20 | 184 / 245 | 93% | 63.40 | 466 / 502 |
esophagus | 82% | 14862.58 | 1186 / 1445 | 82% | 45.59 | 150 / 183 |
intestine | 79% | 12101.11 | 765 / 966 | 84% | 69.08 | 441 / 527 |
stomach | 62% | 9029.91 | 223 / 359 | 83% | 58.78 | 237 / 286 |
skin | 79% | 15751.96 | 1422 / 1809 | 57% | 22.83 | 269 / 472 |
adipose | 100% | 59581.43 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 52.93 | 29 / 29 |
uterus | 21% | 3206.82 | 36 / 170 | 76% | 41.93 | 348 / 459 |
heart | 89% | 18687.55 | 768 / 861 | 0% | 0 | 0 / 0 |
ovary | 19% | 2046.81 | 34 / 180 | 70% | 25.10 | 301 / 430 |
tonsil | 0% | 0 | 0 / 0 | 89% | 42.97 | 40 / 45 |
pancreas | 1% | 63.34 | 4 / 328 | 87% | 55.62 | 154 / 178 |
kidney | 2% | 181.54 | 2 / 89 | 79% | 43.94 | 709 / 901 |
blood vessel | 75% | 12945.52 | 998 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 54% | 13.73 | 43 / 80 |
muscle | 51% | 3865.56 | 413 / 803 | 0% | 0 | 0 / 0 |
adrenal gland | 5% | 330.69 | 14 / 258 | 39% | 12.40 | 90 / 230 |
liver | 0% | 0 | 0 / 226 | 38% | 11.93 | 156 / 406 |
brain | 0% | 1.84 | 1 / 2642 | 35% | 12.15 | 247 / 705 |
peripheral blood | 29% | 3511.10 | 273 / 929 | 0% | 0 | 0 / 0 |
spleen | 1% | 54.84 | 3 / 241 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006957 | Biological process | complement activation, alternative pathway |
GO_0006956 | Biological process | complement activation |
GO_0006508 | Biological process | proteolysis |
GO_0009617 | Biological process | response to bacterium |
GO_1904813 | Cellular component | ficolin-1-rich granule lumen |
GO_0070062 | Cellular component | extracellular exosome |
GO_0031093 | Cellular component | platelet alpha granule lumen |
GO_0005576 | Cellular component | extracellular region |
GO_0034774 | Cellular component | secretory granule lumen |
GO_0008236 | Molecular function | serine-type peptidase activity |
GO_0004252 | Molecular function | serine-type endopeptidase activity |
Gene name | CFD |
Protein name | Complement factor D (EC 3.4.21.46) (Adipsin) (C3 convertase activator) (Properdin factor D) |
Synonyms | DF PFD |
Description | FUNCTION: Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. FUNCTION: Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. . FUNCTION: Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. . FUNCTION: Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. . FUNCTION: Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. . |
Accessions | ENST00000327726.11 ENST00000695942.1 K7ERG9 ENST00000695945.1 ENST00000695943.1 A0A8Q3WKV6 ENST00000695946.1 ENST00000592860.3 ENST00000617994.2 ENST00000695944.1 P00746 A0A8Q3WKW0 A0A8Q3WLE6 ENST00000632706.1 |