I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| hepatocyte | 5 studies | 59% ± 14% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| hepatocyte | 5 studies | 59% ± 14% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| liver | 3 studies | 31% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 23186.74 | 226 / 226 | 95% | 219.99 | 387 / 406 |
| lung | 84% | 13.03 | 484 / 578 | 4% | 0.77 | 49 / 1155 |
| pancreas | 70% | 6.82 | 229 / 328 | 5% | 0.22 | 9 / 178 |
| kidney | 67% | 15.28 | 60 / 89 | 0% | 0.35 | 4 / 901 |
| stomach | 59% | 6.25 | 213 / 359 | 4% | 0.39 | 12 / 286 |
| bladder | 43% | 1.38 | 9 / 21 | 1% | 0.03 | 3 / 504 |
| spleen | 42% | 32.20 | 102 / 241 | 0% | 0 | 0 / 0 |
| thymus | 34% | 2.02 | 219 / 653 | 6% | 0.37 | 39 / 605 |
| adrenal gland | 39% | 2.09 | 101 / 258 | 0% | 0 | 0 / 230 |
| peripheral blood | 36% | 10.86 | 336 / 929 | 0% | 0 | 0 / 0 |
| uterus | 34% | 1.65 | 58 / 170 | 0% | 0.01 | 1 / 459 |
| prostate | 34% | 1.17 | 83 / 245 | 0% | 0 | 0 / 502 |
| esophagus | 31% | 1.72 | 450 / 1445 | 2% | 0.11 | 4 / 183 |
| ovary | 31% | 1.32 | 56 / 180 | 0% | 0.40 | 1 / 430 |
| intestine | 29% | 1.61 | 283 / 966 | 1% | 0.78 | 5 / 527 |
| adipose | 28% | 4.42 | 337 / 1204 | 0% | 0 | 0 / 0 |
| breast | 27% | 3.07 | 125 / 459 | 0% | 0.14 | 1 / 1118 |
| skin | 27% | 2.21 | 484 / 1809 | 0% | 0.02 | 1 / 472 |
| heart | 25% | 1.49 | 212 / 861 | 0% | 0 | 0 / 0 |
| brain | 24% | 0.83 | 627 / 2642 | 0% | 0 | 0 / 705 |
| blood vessel | 23% | 1.22 | 311 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 19% | 0.70 | 150 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006955 | Biological process | immune response |
| GO_0031640 | Biological process | killing of cells of another organism |
| GO_0050778 | Biological process | positive regulation of immune response |
| GO_0006957 | Biological process | complement activation, alternative pathway |
| GO_0006958 | Biological process | complement activation, classical pathway |
| GO_0006956 | Biological process | complement activation |
| GO_0005615 | Cellular component | extracellular space |
| GO_0072562 | Cellular component | blood microparticle |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005579 | Cellular component | membrane attack complex |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0044877 | Molecular function | protein-containing complex binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0001848 | Molecular function | complement binding |
| Gene name | C8A |
| Protein name | Complement component C8 alpha chain (Complement component 8 subunit alpha) C8A protein Complement C8 alpha chain |
| Synonyms | |
| Description | FUNCTION: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself. . |
| Accessions | A0A8Q3WKT7 Q05CV2 ENST00000695723.1 ENST00000695677.1 A0A8Q3WKQ2 A0A8Q3WKN4 P07357 A0A8Q3WL79 A0A8Q3WKN0 ENST00000695681.1 ENST00000695679.1 ENST00000695678.1 ENST00000361249.4 |
