CFHR1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CFHR1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CFHR1 at tissue level.

III. Associated gene sets

GO_0032091Biological processnegative regulation of protein binding
GO_0006956Biological processcomplement activation
GO_0051838Biological processcytolysis by host of symbiont cells
GO_0005615Cellular componentextracellular space
GO_0072562Cellular componentblood microparticle
GO_0032991Cellular componentprotein-containing complex
GO_0005576Cellular componentextracellular region
GO_0001851Molecular functioncomplement component C3b binding
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCFHR1
Protein nameComplement factor H-related protein 1 (FHR-1) (H factor-like protein 1) (FHL-1) (H-factor-like 1) (H36)
Complement factor H related 1
SynonymsCFHL
CFHL1P
HFL1
HFL2
CFHL1
CFHR1P
FHR1
DescriptionFUNCTION: Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism. .

AccessionsB1AKG0
A0A8V8TNS5
ENST00000699454.1
ENST00000699455.1
Q03591
ENST00000320493.10
A0A8V8TQ26
ENST00000367424.4