CFHR2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CFHR2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CFHR2 at tissue level.

III. Associated gene sets

GO_0032091Biological processnegative regulation of protein binding
GO_0006956Biological processcomplement activation
GO_0051838Biological processcytolysis by host of symbiont cells
GO_0005615Cellular componentextracellular space
GO_0032991Cellular componentprotein-containing complex
GO_0005576Cellular componentextracellular region
GO_0001851Molecular functioncomplement component C3b binding
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCFHR2
Protein nameComplement factor H related 2
Complement factor H-related protein 2 (FHR-2) (DDESK59) (H factor-like 3) (H factor-like protein 2)
SynonymsFHR2
HFL3
CFHL2
DescriptionFUNCTION: Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism. .

AccessionsP36980
A0A3B3IRW0
ENST00000496448.6
V9GYE7
ENST00000649960.2
ENST00000367421.5
ENST00000367415.8 [P36980-1]
ENST00000476712.6
A0A8V8TQS1
ENST00000699921.1
ENST00000489703.2
A0A8V8TPL2
A0A3B3IQ51
A0A3B3ISW6
A0A3B3IS00
ENST00000649283.1
ENST00000473386.1
A0A3B3IS28
ENST00000709546.1 [P36980-1]