Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 38 studies | 47% ± 16% | |
conventional dendritic cell | 23 studies | 41% ± 16% | |
non-classical monocyte | 22 studies | 44% ± 13% | |
classical monocyte | 20 studies | 24% ± 8% | |
dendritic cell | 19 studies | 44% ± 17% | |
monocyte | 12 studies | 34% ± 11% | |
mast cell | 11 studies | 23% ± 5% | |
myeloid cell | 8 studies | 46% ± 15% | |
basal cell | 8 studies | 31% ± 8% | |
alveolar macrophage | 7 studies | 62% ± 21% | |
type I pneumocyte | 7 studies | 31% ± 13% | |
secretory cell | 7 studies | 31% ± 9% | |
epithelial cell | 7 studies | 37% ± 11% | |
mononuclear phagocyte | 6 studies | 40% ± 12% | |
leukocyte | 6 studies | 26% ± 10% | |
respiratory goblet cell | 5 studies | 28% ± 17% | |
microglial cell | 5 studies | 38% ± 20% | |
club cell | 4 studies | 30% ± 10% | |
neutrophil | 4 studies | 28% ± 7% | |
squamous epithelial cell | 3 studies | 36% ± 25% | |
ciliated cell | 3 studies | 25% ± 7% | |
luminal cell of prostate epithelium | 3 studies | 24% ± 7% | |
monocyte-derived dendritic cell | 3 studies | 64% ± 14% | |
inflammatory macrophage | 3 studies | 36% ± 11% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 9 studies | 26% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
stomach | 99% | 1959.09 | 357 / 359 | 100% | 169.90 | 286 / 286 |
lung | 100% | 7580.58 | 578 / 578 | 99% | 137.39 | 1142 / 1155 |
prostate | 99% | 1734.50 | 243 / 245 | 98% | 55.50 | 493 / 502 |
kidney | 100% | 2296.51 | 89 / 89 | 93% | 113.81 | 838 / 901 |
ovary | 94% | 909.38 | 169 / 180 | 99% | 175.86 | 425 / 430 |
breast | 96% | 2072.20 | 441 / 459 | 96% | 91.61 | 1074 / 1118 |
thymus | 98% | 1181.11 | 643 / 653 | 93% | 64.48 | 565 / 605 |
intestine | 93% | 1369.90 | 894 / 966 | 99% | 136.52 | 522 / 527 |
esophagus | 89% | 1356.79 | 1289 / 1445 | 100% | 134.92 | 183 / 183 |
pancreas | 89% | 1072.92 | 291 / 328 | 97% | 139.96 | 172 / 178 |
uterus | 88% | 831.18 | 150 / 170 | 91% | 100.96 | 418 / 459 |
bladder | 81% | 1134.86 | 17 / 21 | 90% | 83.63 | 455 / 504 |
liver | 89% | 1973.67 | 201 / 226 | 81% | 65.85 | 330 / 406 |
brain | 72% | 904.47 | 1891 / 2642 | 97% | 92.54 | 685 / 705 |
skin | 76% | 1641.37 | 1383 / 1809 | 74% | 43.87 | 348 / 472 |
adrenal gland | 100% | 1940.97 | 258 / 258 | 44% | 15.53 | 101 / 230 |
spleen | 100% | 4791.58 | 241 / 241 | 0% | 0 | 0 / 0 |
adipose | 98% | 2266.44 | 1182 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 90.27 | 44 / 45 |
blood vessel | 95% | 2001.35 | 1266 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 81% | 5969.23 | 756 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 79% | 67.34 | 23 / 29 |
heart | 37% | 334.41 | 315 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 33% | 11.55 | 26 / 80 |
muscle | 2% | 14.08 | 18 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007165 | Biological process | signal transduction |
GO_0034097 | Biological process | response to cytokine |
GO_0010818 | Biological process | T cell chemotaxis |
GO_0034341 | Biological process | response to type II interferon |
GO_0030335 | Biological process | positive regulation of cell migration |
GO_0006935 | Biological process | chemotaxis |
GO_0034612 | Biological process | response to tumor necrosis factor |
GO_0006898 | Biological process | receptor-mediated endocytosis |
GO_0030307 | Biological process | positive regulation of cell growth |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0005041 | Molecular function | low-density lipoprotein particle receptor activity |
GO_0008009 | Molecular function | chemokine activity |
GO_0005044 | Molecular function | scavenger receptor activity |
Gene name | CXCL16 |
Protein name | C-X-C motif chemokine 16 (Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein) (SR-PSOX) (Small-inducible cytokine B16) (Transmembrane chemokine CXCL16) C-X-C motif chemokine 16 (Transmembrane chemokine CXCL16) C-X-C motif chemokine ligand 16 |
Synonyms | SRPSOX SCYB16 UNQ2759/PRO6714 |
Description | FUNCTION: Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. . |
Accessions | I3L333 ENST00000573123.1 ENST00000576153.5 A0A6I8PIU7 ENST00000574412.6 ENST00000293778.12 Q9H2A7 |