CXCL16 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0034097Biological processresponse to cytokine
GO_0010818Biological processT cell chemotaxis
GO_0034341Biological processresponse to type II interferon
GO_0030335Biological processpositive regulation of cell migration
GO_0006935Biological processchemotaxis
GO_0034612Biological processresponse to tumor necrosis factor
GO_0006898Biological processreceptor-mediated endocytosis
GO_0030307Biological processpositive regulation of cell growth
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005041Molecular functionlow-density lipoprotein particle receptor activity
GO_0008009Molecular functionchemokine activity
GO_0005044Molecular functionscavenger receptor activity

IV. Literature review

[source]
Gene nameCXCL16
Protein nameC-X-C motif chemokine 16 (Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein) (SR-PSOX) (Small-inducible cytokine B16) (Transmembrane chemokine CXCL16)
C-X-C motif chemokine 16 (Transmembrane chemokine CXCL16)
C-X-C motif chemokine ligand 16
SynonymsSRPSOX
SCYB16
UNQ2759/PRO6714
DescriptionFUNCTION: Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. .

AccessionsI3L333
ENST00000573123.1
ENST00000576153.5
A0A6I8PIU7
ENST00000574412.6
ENST00000293778.12
Q9H2A7