SHROOM3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0043482Biological processcellular pigment accumulation
GO_0007015Biological processactin filament organization
GO_0008360Biological processregulation of cell shape
GO_0000902Biological processcell morphogenesis
GO_0045176Biological processapical protein localization
GO_0007389Biological processpattern specification process
GO_0016324Cellular componentapical plasma membrane
GO_0043296Cellular componentapical junction complex
GO_0005856Cellular componentcytoskeleton
GO_0005912Cellular componentadherens junction
GO_0030864Cellular componentcortical actin cytoskeleton
GO_0005874Cellular componentmicrotubule
GO_0051015Molecular functionactin filament binding

IV. Literature review

[source]
Gene nameSHROOM3
Protein nameProtein Shroom3 (Shroom-related protein) (hShrmL)
Shroom family member 3
SynonymsSHRML
KIAA1481
MSTP013
DescriptionFUNCTION: Controls cell shape changes in the neuroepithelium during neural tube closure. Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myosin II, and probably by bundling stress fibers (By similarity). Induces apicobasal cell elongation by redistributing gamma-tubulin and directing the assembly of robust apicobasal microtubule arrays (By similarity). .

AccessionsENST00000644244.1
ENST00000296043.7 [Q8TF72-1]
A0A2R8Y7T7
ENST00000646790.1
Q8TF72
A0A2R8Y5P9