Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 39 studies | 35% ± 14% | |
pericyte | 18 studies | 25% ± 8% | |
fibroblast | 17 studies | 23% ± 7% | |
epithelial cell | 14 studies | 35% ± 20% | |
connective tissue cell | 12 studies | 23% ± 8% | |
endothelial cell of vascular tree | 12 studies | 37% ± 13% | |
basal cell | 12 studies | 31% ± 12% | |
vein endothelial cell | 11 studies | 37% ± 7% | |
endothelial cell of lymphatic vessel | 10 studies | 29% ± 12% | |
macrophage | 10 studies | 23% ± 8% | |
endothelial cell of artery | 10 studies | 33% ± 13% | |
capillary endothelial cell | 10 studies | 36% ± 10% | |
type I pneumocyte | 9 studies | 30% ± 10% | |
secretory cell | 9 studies | 30% ± 12% | |
smooth muscle cell | 9 studies | 19% ± 3% | |
mesothelial cell | 8 studies | 48% ± 22% | |
dendritic cell | 6 studies | 27% ± 6% | |
myofibroblast cell | 5 studies | 25% ± 7% | |
myeloid cell | 5 studies | 23% ± 7% | |
type II pneumocyte | 5 studies | 22% ± 4% | |
ciliated cell | 5 studies | 34% ± 11% | |
abnormal cell | 5 studies | 25% ± 6% | |
squamous epithelial cell | 4 studies | 45% ± 21% | |
podocyte | 4 studies | 55% ± 24% | |
club cell | 4 studies | 24% ± 9% | |
enterocyte | 4 studies | 19% ± 2% | |
luminal hormone-sensing cell of mammary gland | 4 studies | 50% ± 11% | |
luminal cell of prostate epithelium | 4 studies | 24% ± 7% | |
enteroendocrine cell | 4 studies | 29% ± 13% | |
goblet cell | 4 studies | 26% ± 7% | |
monocyte | 3 studies | 27% ± 6% | |
respiratory goblet cell | 3 studies | 32% ± 17% | |
conventional dendritic cell | 3 studies | 19% ± 5% | |
progenitor cell | 3 studies | 23% ± 4% | |
renal alpha-intercalated cell | 3 studies | 23% ± 5% | |
retinal pigment epithelial cell | 3 studies | 22% ± 8% | |
myoepithelial cell | 3 studies | 36% ± 10% | |
astrocyte | 3 studies | 16% ± 1% | |
mononuclear phagocyte | 3 studies | 27% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 3578.44 | 180 / 180 | 100% | 191.31 | 430 / 430 |
liver | 100% | 4836.64 | 226 / 226 | 100% | 146.90 | 405 / 406 |
prostate | 100% | 5771.98 | 245 / 245 | 100% | 224.71 | 500 / 502 |
breast | 100% | 6219.72 | 459 / 459 | 99% | 220.86 | 1112 / 1118 |
pancreas | 100% | 2482.46 | 328 / 328 | 99% | 161.51 | 177 / 178 |
intestine | 100% | 3335.07 | 966 / 966 | 99% | 133.46 | 524 / 527 |
stomach | 100% | 4823.27 | 359 / 359 | 99% | 145.92 | 283 / 286 |
esophagus | 100% | 3934.06 | 1444 / 1445 | 99% | 144.29 | 181 / 183 |
lung | 100% | 6339.08 | 578 / 578 | 99% | 115.89 | 1140 / 1155 |
uterus | 100% | 3921.18 | 170 / 170 | 99% | 123.97 | 453 / 459 |
kidney | 100% | 5455.30 | 89 / 89 | 98% | 80.14 | 884 / 901 |
bladder | 100% | 2938.05 | 21 / 21 | 97% | 120.24 | 491 / 504 |
thymus | 100% | 5393.04 | 653 / 653 | 95% | 98.24 | 573 / 605 |
skin | 100% | 4341.56 | 1809 / 1809 | 92% | 59.46 | 434 / 472 |
adrenal gland | 100% | 5884.02 | 258 / 258 | 92% | 81.66 | 211 / 230 |
brain | 77% | 985.50 | 2042 / 2642 | 70% | 36.45 | 492 / 705 |
adipose | 100% | 5345.60 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 4741.89 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 236.72 | 1 / 1 |
blood vessel | 100% | 2877.12 | 1331 / 1335 | 0% | 0 | 0 / 0 |
heart | 100% | 3099.19 | 857 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 67.50 | 79 / 80 |
tonsil | 0% | 0 | 0 / 0 | 98% | 78.61 | 44 / 45 |
muscle | 78% | 887.21 | 629 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 66% | 43.89 | 19 / 29 |
peripheral blood | 49% | 1054.03 | 451 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0033005 | Biological process | positive regulation of mast cell activation |
GO_0050862 | Biological process | positive regulation of T cell receptor signaling pathway |
GO_0045954 | Biological process | positive regulation of natural killer cell mediated cytotoxicity |
GO_0060370 | Biological process | susceptibility to T cell mediated cytotoxicity |
GO_0002891 | Biological process | positive regulation of immunoglobulin mediated immune response |
GO_0007010 | Biological process | cytoskeleton organization |
GO_0007289 | Biological process | spermatid nucleus differentiation |
GO_0051649 | Biological process | establishment of localization in cell |
GO_0046718 | Biological process | symbiont entry into host cell |
GO_0009566 | Biological process | fertilization |
GO_0019064 | Biological process | fusion of virus membrane with host plasma membrane |
GO_0007156 | Biological process | homophilic cell adhesion via plasma membrane adhesion molecules |
GO_0001675 | Biological process | acrosome assembly |
GO_0044782 | Biological process | cilium organization |
GO_0044406 | Biological process | adhesion of symbiont to host |
GO_0030382 | Biological process | sperm mitochondrion organization |
GO_0002860 | Biological process | positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target |
GO_0046814 | Biological process | coreceptor-mediated virion attachment to host cell |
GO_0042271 | Biological process | susceptibility to natural killer cell mediated cytotoxicity |
GO_0046596 | Biological process | regulation of viral entry into host cell |
GO_0007286 | Biological process | spermatid development |
GO_0051654 | Biological process | establishment of mitochondrion localization |
GO_0005915 | Cellular component | zonula adherens |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0044291 | Cellular component | cell-cell contact zone |
GO_0005925 | Cellular component | focal adhesion |
GO_0005911 | Cellular component | cell-cell junction |
GO_0009986 | Cellular component | cell surface |
GO_0043296 | Cellular component | apical junction complex |
GO_0015026 | Molecular function | coreceptor activity |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0001618 | Molecular function | virus receptor activity |
GO_0050839 | Molecular function | cell adhesion molecule binding |
GO_0005515 | Molecular function | protein binding |
Gene name | NECTIN2 |
Protein name | Poliovirus receptor related 2 Nectin cell adhesion molecule 2 Nectin-2 (Herpes virus entry mediator B) (Herpesvirus entry mediator B) (HveB) (Nectin cell adhesion molecule 2) (Poliovirus receptor-related protein 2) (CD antigen CD112) |
Synonyms | PRR2 HVEB PVRL2 |
Description | FUNCTION: Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive . Probable cell adhesion protein . .; FUNCTION: (Microbial infection) Acts as a receptor for herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV). . |
Accessions | ENST00000592018.1 Q7Z456 ENST00000591581.1 Q7Z458 ENST00000252483.10 [Q92692-1] Q92692 K7EKE8 Q7Z457 K7EK87 K7ERL3 ENST00000252485.8 [Q92692-2] ENST00000585601.1 |