positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target

I. Involved cell types

Genes
Cell types
No. of supported studies
Group 1
CRTAM
lymphocyte
7 studies
Group 2
PVRNECTIN2
dopaminergic neuron
6 studies
Group 3
CD226
hematopoietic stem cellneuronlymphocyte
20 studies

II. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1CD226-NECTIN2CD226_HUMAN - PVRL2_HUMANAdhesion-Adhesion
2PVR-CD226PVR_HUMAN - CD226_HUMANLigand-ReceptorSignaling by Poliovirus receptor

III. Literature review

[source]
Namepositive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
IDGO_0002860
collection_id

Biological process

Exact synonym

up regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, up-regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, upregulation of natural killer cell mediated cytotoxicity directed against tumor cell target

Description

Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.

External URL
Genes
CRTAMIL12ACD226IL12BPVRNECTIN2