CD226 | OmnibusX

Name	Number of supported studies	Average coverage
natural killer cell	11 studies	22% ± 6%	Explore
CD16-positive, CD56-dim natural killer cell, human	9 studies	21% ± 6%	Explore
platelet	8 studies	32% ± 9%	Explore
T cell	7 studies	25% ± 6%	Explore
CD4-positive, alpha-beta T cell	7 studies	23% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	6 studies	19% ± 5%	Explore
mature NK T cell	6 studies	19% ± 3%	Explore
CD8-positive, alpha-beta T cell	5 studies	21% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	26% ± 5%	Explore
dendritic cell	3 studies	16% ± 0%	Explore
megakaryocyte	3 studies	42% ± 7%	Explore
lymphocyte	3 studies	33% ± 12%	Explore
microglial cell	3 studies	25% ± 7%	Explore

Name	Number of supported studies	Average coverage
brain	3 studies	27% ± 10%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	558.41	578 / 578	38%	0.77	444 / 1155
kidney	97%	153.25	86 / 89	38%	0.68	343 / 901
breast	87%	96.89	398 / 459	32%	0.62	361 / 1118
thymus	99%	193.78	645 / 653	18%	0.29	106 / 605
stomach	94%	123.92	339 / 359	20%	0.40	58 / 286
uterus	97%	122.02	165 / 170	16%	0.32	75 / 459
bladder	95%	162.48	20 / 21	11%	0.21	54 / 504
intestine	94%	201.40	907 / 966	11%	0.33	60 / 527
brain	88%	131.29	2315 / 2642	16%	0.29	110 / 705
prostate	97%	121.00	237 / 245	6%	0.10	29 / 502
liver	96%	127.85	216 / 226	6%	0.11	26 / 406
esophagus	81%	76.77	1175 / 1445	19%	0.32	35 / 183
skin	71%	57.25	1284 / 1809	29%	0.60	137 / 472
spleen	100%	1881.11	241 / 241	0%	0	0 / 0
peripheral blood	99%	3747.22	920 / 929	0%	0	0 / 0
adipose	96%	127.75	1160 / 1204	0%	0	0 / 0
ovary	92%	108.95	165 / 180	3%	0.04	13 / 430
adrenal gland	81%	60.42	210 / 258	3%	0.09	6 / 230
blood vessel	84%	91.10	1119 / 1335	0%	0	0 / 0
pancreas	44%	27.91	143 / 328	26%	0.42	47 / 178
heart	66%	47.63	566 / 861	0%	0	0 / 0
muscle	65%	53.01	518 / 803	0%	0	0 / 0
lymph node	0%	0	0 / 0	62%	2.16	18 / 29
tonsil	0%	0	0 / 0	44%	0.77	20 / 45
eye	0%	0	0 / 0	41%	0.86	33 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0033005	Biological process	positive regulation of mast cell activation
GO_0050862	Biological process	positive regulation of T cell receptor signaling pathway
GO_0045954	Biological process	positive regulation of natural killer cell mediated cytotoxicity
GO_0007165	Biological process	signal transduction
GO_0060369	Biological process	positive regulation of Fc receptor mediated stimulatory signaling pathway
GO_0001816	Biological process	cytokine production
GO_0002891	Biological process	positive regulation of immunoglobulin mediated immune response
GO_0007155	Biological process	cell adhesion
GO_0002729	Biological process	positive regulation of natural killer cell cytokine production
GO_0008037	Biological process	cell recognition
GO_0002860	Biological process	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO_0032729	Biological process	positive regulation of type II interferon production
GO_0009897	Cellular component	external side of plasma membrane
GO_0005886	Cellular component	plasma membrane
GO_0045121	Cellular component	membrane raft
GO_0009986	Cellular component	cell surface
GO_0019901	Molecular function	protein kinase binding
GO_0042802	Molecular function	identical protein binding
GO_0005178	Molecular function	integrin binding
GO_0050839	Molecular function	cell adhesion molecule binding
GO_0005515	Molecular function	protein binding

Gene name	CD226
Protein name	CD226 molecule CD226 antigen (DNAX accessory molecule 1) (DNAM-1) (CD antigen CD226)
Synonyms	DNAM1
Description	FUNCTION: Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell . Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding . .
Accessions	ENST00000280200.8 ENST00000582621.6 J3QR77 ENST00000578928.1 J3QRQ4 ENST00000583955.5 J3QL19 J3QQW1 ENST00000579496.5 ENST00000581982.5 Q15762 ENST00000577287.5 ENST00000580335.1 J3QKM7

CD226 report