Name | Number of supported studies | Average coverage | |
---|---|---|---|
type I pneumocyte | 11 studies | 49% ± 28% | |
astrocyte | 11 studies | 31% ± 17% | |
endothelial cell | 11 studies | 33% ± 17% | |
glutamatergic neuron | 10 studies | 57% ± 21% | |
ciliated cell | 10 studies | 37% ± 19% | |
GABAergic neuron | 9 studies | 47% ± 22% | |
epithelial cell | 9 studies | 51% ± 24% | |
basal cell | 9 studies | 49% ± 26% | |
adipocyte | 8 studies | 28% ± 6% | |
fibroblast | 8 studies | 29% ± 12% | |
retinal ganglion cell | 7 studies | 53% ± 26% | |
endothelial cell of lymphatic vessel | 7 studies | 25% ± 12% | |
club cell | 6 studies | 50% ± 26% | |
cardiac muscle cell | 6 studies | 60% ± 22% | |
T cell | 6 studies | 36% ± 12% | |
mesothelial cell | 5 studies | 49% ± 14% | |
type II pneumocyte | 5 studies | 57% ± 21% | |
goblet cell | 5 studies | 33% ± 30% | |
interneuron | 5 studies | 53% ± 16% | |
neuron | 4 studies | 51% ± 26% | |
oligodendrocyte | 4 studies | 28% ± 17% | |
CD4-positive, alpha-beta T cell | 4 studies | 30% ± 10% | |
lymphocyte | 4 studies | 36% ± 11% | |
amacrine cell | 4 studies | 32% ± 5% | |
retina horizontal cell | 4 studies | 35% ± 12% | |
retinal rod cell | 4 studies | 32% ± 12% | |
respiratory goblet cell | 4 studies | 52% ± 26% | |
smooth muscle cell | 4 studies | 30% ± 4% | |
kidney loop of Henle epithelial cell | 4 studies | 45% ± 30% | |
secretory cell | 3 studies | 24% ± 7% | |
oligodendrocyte precursor cell | 3 studies | 27% ± 4% | |
microglial cell | 3 studies | 31% ± 18% | |
squamous epithelial cell | 3 studies | 48% ± 21% | |
GABAergic amacrine cell | 3 studies | 27% ± 8% | |
OFF-bipolar cell | 3 studies | 43% ± 19% | |
ON-bipolar cell | 3 studies | 40% ± 20% | |
glycinergic amacrine cell | 3 studies | 22% ± 5% | |
retinal cone cell | 3 studies | 23% ± 5% | |
retinal pigment epithelial cell | 3 studies | 45% ± 33% | |
ependymal cell | 3 studies | 43% ± 14% | |
enteroendocrine cell | 3 studies | 18% ± 2% | |
granule cell | 3 studies | 58% ± 22% | |
renal principal cell | 3 studies | 62% ± 26% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 3820.40 | 245 / 245 | 100% | 23.96 | 501 / 502 |
esophagus | 100% | 3333.55 | 1438 / 1445 | 100% | 30.06 | 183 / 183 |
ovary | 100% | 2024.34 | 180 / 180 | 99% | 15.29 | 426 / 430 |
intestine | 100% | 2363.05 | 962 / 966 | 99% | 19.19 | 522 / 527 |
pancreas | 100% | 2533.33 | 327 / 328 | 99% | 17.13 | 176 / 178 |
lung | 99% | 2203.93 | 573 / 578 | 99% | 19.11 | 1147 / 1155 |
kidney | 100% | 4986.27 | 89 / 89 | 98% | 25.15 | 884 / 901 |
stomach | 100% | 2466.65 | 358 / 359 | 98% | 19.56 | 280 / 286 |
thymus | 100% | 4222.33 | 653 / 653 | 96% | 24.81 | 583 / 605 |
breast | 96% | 2920.35 | 442 / 459 | 99% | 36.95 | 1109 / 1118 |
uterus | 100% | 1869.89 | 170 / 170 | 93% | 16.86 | 429 / 459 |
bladder | 95% | 2543.05 | 20 / 21 | 97% | 17.67 | 488 / 504 |
liver | 99% | 1571.29 | 224 / 226 | 82% | 9.60 | 332 / 406 |
adrenal gland | 97% | 1811.34 | 251 / 258 | 59% | 5.55 | 135 / 230 |
brain | 71% | 2809.34 | 1866 / 2642 | 50% | 3.44 | 351 / 705 |
skin | 87% | 3435.67 | 1576 / 1809 | 22% | 1.44 | 106 / 472 |
tonsil | 0% | 0 | 0 / 0 | 100% | 15.79 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.20 | 1 / 1 |
muscle | 100% | 2905.75 | 802 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2372.86 | 1331 / 1335 | 0% | 0 | 0 / 0 |
heart | 95% | 4140.99 | 814 / 861 | 0% | 0 | 0 / 0 |
adipose | 92% | 1057.79 | 1110 / 1204 | 0% | 0 | 0 / 0 |
spleen | 78% | 694.51 | 188 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 30% | 387.48 | 280 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 7% | 0.31 | 2 / 29 |
eye | 0% | 0 | 0 / 0 | 6% | 0.34 | 5 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0035089 | Biological process | establishment of apical/basal cell polarity |
GO_0045197 | Biological process | establishment or maintenance of epithelial cell apical/basal polarity |
GO_0035556 | Biological process | intracellular signal transduction |
GO_0120192 | Biological process | tight junction assembly |
GO_0016324 | Cellular component | apical plasma membrane |
GO_0030054 | Cellular component | cell junction |
GO_0043296 | Cellular component | apical junction complex |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005829 | Cellular component | cytosol |
GO_0045177 | Cellular component | apical part of cell |
GO_0005886 | Cellular component | plasma membrane |
GO_0034451 | Cellular component | centriolar satellite |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0005737 | Cellular component | cytoplasm |
GO_0005923 | Cellular component | bicellular tight junction |
GO_0005515 | Molecular function | protein binding |
Gene name | PATJ |
Protein name | PATJ crumbs cell polarity complex component INADL protein InaD-like protein (Inadl protein) (hINADL) (Channel-interacting PDZ domain-containing protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) PATJ crumbs cell polarity complex component (cDNA FLJ59473, highly similar to InaD-like protein) |
Synonyms | CIPP INADL |
Description | FUNCTION: Scaffolding protein that facilitates the localization of proteins to the cell membrane . Required for the correct formation of tight junctions and epithelial apico-basal polarity . Positively regulates epithelial cell microtubule elongation and cell migration, possibly via facilitating localization of PRKCI/aPKC and PAR3D/PAR3 at the leading edge of migrating cells (By similarity). Plays a role in the correct reorientation of the microtubule-organizing center during epithelial migration (By similarity). May regulate the surface expression and/or function of ASIC3 in sensory neurons (By similarity). May recruit ARHGEF18 to apical cell-cell boundaries . . |
Accessions | A0A0U1RQR3 A0A0U1RQT2 ENST00000371158.6 [Q8NI35-1] A0A2R8Y5I3 ENST00000635137.1 ENST00000465798.2 Q8NI35 A0A0U1RR46 ENST00000484937.5 [Q8NI35-5] A0A2R8Y549 ENST00000307297.8 B4DE90 ENST00000494842.2 ENST00000646453.1 ENST00000490547.2 A5PKX9 ENST00000635023.1 A0A0U1RQW4 A0A0U1RRD7 ENST00000642238.2 |