I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| oligodendrocyte precursor cell | 4 studies | 27% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| oligodendrocyte precursor cell | 4 studies | 27% ± 4% |
Insufficient scRNA-seq data for expression of SAPCD2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 99% | 623.79 | 2606 / 2642 | 91% | 36.14 | 642 / 705 |
| prostate | 82% | 388.63 | 201 / 245 | 97% | 18.85 | 486 / 502 |
| stomach | 64% | 212.67 | 231 / 359 | 96% | 40.14 | 275 / 286 |
| intestine | 49% | 268.87 | 469 / 966 | 96% | 45.83 | 506 / 527 |
| skin | 92% | 712.23 | 1671 / 1809 | 51% | 5.35 | 243 / 472 |
| esophagus | 39% | 340.46 | 565 / 1445 | 97% | 34.04 | 178 / 183 |
| breast | 53% | 124.95 | 242 / 459 | 78% | 12.31 | 874 / 1118 |
| bladder | 29% | 31.00 | 6 / 21 | 86% | 23.84 | 432 / 504 |
| lung | 28% | 52.25 | 162 / 578 | 77% | 14.82 | 887 / 1155 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 27.78 | 45 / 45 |
| uterus | 6% | 15.31 | 11 / 170 | 92% | 20.63 | 424 / 459 |
| spleen | 97% | 269.80 | 234 / 241 | 0% | 0 | 0 / 0 |
| ovary | 1% | 2.18 | 1 / 180 | 81% | 12.75 | 347 / 430 |
| lymph node | 0% | 0 | 0 / 0 | 79% | 11.19 | 23 / 29 |
| kidney | 66% | 128.25 | 59 / 89 | 8% | 0.88 | 70 / 901 |
| pancreas | 3% | 5.35 | 11 / 328 | 61% | 6.61 | 109 / 178 |
| peripheral blood | 57% | 251.36 | 530 / 929 | 0% | 0 | 0 / 0 |
| adrenal gland | 9% | 11.67 | 23 / 258 | 24% | 2.30 | 56 / 230 |
| thymus | 11% | 14.48 | 73 / 653 | 10% | 0.91 | 61 / 605 |
| liver | 2% | 2.31 | 5 / 226 | 11% | 1.11 | 45 / 406 |
| adipose | 7% | 14.82 | 90 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 3% | 3.68 | 34 / 1335 | 0% | 0 | 0 / 0 |
| heart | 2% | 2.50 | 14 / 861 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0.30 | 2 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0000132 | Biological process | establishment of mitotic spindle orientation |
| GO_0098725 | Biological process | symmetric cell division |
| GO_0090175 | Biological process | regulation of establishment of planar polarity |
| GO_1904777 | Biological process | negative regulation of protein localization to cell cortex |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0005730 | Cellular component | nucleolus |
| GO_0043296 | Cellular component | apical junction complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0045179 | Cellular component | apical cortex |
| GO_0005923 | Cellular component | bicellular tight junction |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SAPCD2 |
| Protein name | Suppressor APC domain-containing protein 2 (Tumor specificity and mitosis phase-dependent expression protein) (TS/MDEP) (p42.3) |
| Synonyms | C9orf140 |
| Description | FUNCTION: Plays a role in planar mitotic spindle orientation in retinal progenitor cells (RPCs) and promotes the production of symmetric terminal divisions (By similarity). Negatively regulates the mitotic apical cortex localization of GPSM2 . Involved also in positive regulation of cell proliferation and tumor cell growth . . |
| Accessions | Q86UD0 ENST00000409687.5 |
