LRRC7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0009790Biological processembryo development
GO_0045197Biological processestablishment or maintenance of epithelial cell apical/basal polarity
GO_0098887Biological processneurotransmitter receptor transport, endosome to postsynaptic membrane
GO_0098609Biological processcell-cell adhesion
GO_0010976Biological processpositive regulation of neuron projection development
GO_0098968Biological processneurotransmitter receptor transport postsynaptic membrane to endosome
GO_0043113Biological processreceptor clustering
GO_0005829Cellular componentcytosol
GO_0005912Cellular componentadherens junction
GO_0005576Cellular componentextracellular region
GO_0014069Cellular componentpostsynaptic density
GO_0035580Cellular componentspecific granule lumen
GO_0043194Cellular componentaxon initial segment
GO_0016323Cellular componentbasolateral plasma membrane
GO_0045211Cellular componentpostsynaptic membrane
GO_0019901Molecular functionprotein kinase binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameLRRC7
Protein nameLRRC7 protein
Leucine rich repeat containing 7 (cDNA FLJ54846, highly similar to Leucine-rich repeat-containing protein 7)
Leucine-rich repeat-containing protein 7 (Densin-180) (Densin) (Protein LAP1)
Leucine rich repeat containing 7
SynonymsLAP1
KIAA1365
DescriptionFUNCTION: Required for normal synaptic spine architecture and function. Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression. .

AccessionsENST00000370958.5
ENST00000608744.5
Q96NW7
A1L1C6
K7ELH5
ENST00000588515.5
A0A494C1A4
B1AKT2
F8WE45
ENST00000310961.9
V9GY23
ENST00000608815.5
V9GZ42
ENST00000415775.2
ENST00000651989.2
A0A075B6E9
V9GYE1
ENST00000609498.5