Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte precursor cell | 14 studies | 72% ± 21% | |
oligodendrocyte | 12 studies | 54% ± 22% | |
glutamatergic neuron | 11 studies | 87% ± 14% | |
GABAergic neuron | 10 studies | 76% ± 23% | |
astrocyte | 9 studies | 39% ± 23% | |
microglial cell | 8 studies | 35% ± 20% | |
interneuron | 6 studies | 71% ± 23% | |
neuron | 5 studies | 56% ± 12% | |
endothelial cell | 5 studies | 47% ± 22% | |
retinal ganglion cell | 4 studies | 40% ± 23% | |
GABAergic interneuron | 3 studies | 84% ± 9% | |
granule cell | 3 studies | 55% ± 31% | |
retinal bipolar neuron | 3 studies | 58% ± 34% | |
glycinergic amacrine cell | 3 studies | 31% ± 5% | |
amacrine cell | 3 studies | 22% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 93% | 2130.59 | 2453 / 2642 | 37% | 0.93 | 258 / 705 |
thymus | 98% | 770.48 | 643 / 653 | 7% | 0.10 | 42 / 605 |
heart | 46% | 169.11 | 395 / 861 | 0% | 0 | 0 / 0 |
prostate | 23% | 57.37 | 57 / 245 | 20% | 0.41 | 98 / 502 |
intestine | 39% | 116.33 | 377 / 966 | 0% | 0.00 | 1 / 527 |
esophagus | 27% | 81.02 | 396 / 1445 | 1% | 0.01 | 1 / 183 |
bladder | 24% | 43.19 | 5 / 21 | 1% | 0.03 | 4 / 504 |
muscle | 20% | 44.57 | 161 / 803 | 0% | 0 | 0 / 0 |
uterus | 15% | 41.75 | 26 / 170 | 3% | 0.18 | 16 / 459 |
kidney | 10% | 17.66 | 9 / 89 | 6% | 0.12 | 58 / 901 |
pancreas | 13% | 27.85 | 43 / 328 | 1% | 0.06 | 2 / 178 |
stomach | 12% | 34.89 | 42 / 359 | 2% | 0.05 | 6 / 286 |
ovary | 5% | 11.69 | 9 / 180 | 1% | 0.02 | 5 / 430 |
breast | 5% | 10.87 | 24 / 459 | 1% | 0.01 | 6 / 1118 |
skin | 4% | 8.08 | 76 / 1809 | 1% | 0.03 | 6 / 472 |
blood vessel | 5% | 13.76 | 70 / 1335 | 0% | 0 | 0 / 0 |
liver | 4% | 6.42 | 8 / 226 | 1% | 0.04 | 5 / 406 |
adipose | 4% | 9.88 | 50 / 1204 | 0% | 0 | 0 / 0 |
adrenal gland | 2% | 3.80 | 5 / 258 | 2% | 0.02 | 4 / 230 |
tonsil | 0% | 0 | 0 / 0 | 2% | 0.04 | 1 / 45 |
lung | 0% | 0.52 | 2 / 578 | 1% | 0.04 | 17 / 1155 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0009790 | Biological process | embryo development |
GO_0045197 | Biological process | establishment or maintenance of epithelial cell apical/basal polarity |
GO_0098887 | Biological process | neurotransmitter receptor transport, endosome to postsynaptic membrane |
GO_0098609 | Biological process | cell-cell adhesion |
GO_0010976 | Biological process | positive regulation of neuron projection development |
GO_0098968 | Biological process | neurotransmitter receptor transport postsynaptic membrane to endosome |
GO_0043113 | Biological process | receptor clustering |
GO_0005829 | Cellular component | cytosol |
GO_0005912 | Cellular component | adherens junction |
GO_0005576 | Cellular component | extracellular region |
GO_0014069 | Cellular component | postsynaptic density |
GO_0035580 | Cellular component | specific granule lumen |
GO_0043194 | Cellular component | axon initial segment |
GO_0016323 | Cellular component | basolateral plasma membrane |
GO_0045211 | Cellular component | postsynaptic membrane |
GO_0019901 | Molecular function | protein kinase binding |
GO_0005515 | Molecular function | protein binding |
Gene name | LRRC7 |
Protein name | LRRC7 protein Leucine rich repeat containing 7 (cDNA FLJ54846, highly similar to Leucine-rich repeat-containing protein 7) Leucine-rich repeat-containing protein 7 (Densin-180) (Densin) (Protein LAP1) Leucine rich repeat containing 7 |
Synonyms | LAP1 KIAA1365 |
Description | FUNCTION: Required for normal synaptic spine architecture and function. Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression. . |
Accessions | ENST00000370958.5 ENST00000608744.5 Q96NW7 A1L1C6 K7ELH5 ENST00000588515.5 A0A494C1A4 B1AKT2 F8WE45 ENST00000310961.9 V9GY23 ENST00000608815.5 V9GZ42 ENST00000415775.2 ENST00000651989.2 A0A075B6E9 V9GYE1 ENST00000609498.5 |