Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 48 studies | 52% ± 27% | |
astrocyte | 17 studies | 44% ± 19% | |
capillary endothelial cell | 16 studies | 35% ± 22% | |
endothelial cell of artery | 15 studies | 45% ± 22% | |
vein endothelial cell | 14 studies | 41% ± 28% | |
oligodendrocyte precursor cell | 13 studies | 38% ± 16% | |
fibroblast | 13 studies | 49% ± 16% | |
microglial cell | 12 studies | 34% ± 21% | |
smooth muscle cell | 11 studies | 46% ± 14% | |
GABAergic neuron | 11 studies | 55% ± 24% | |
pericyte | 11 studies | 39% ± 15% | |
macrophage | 10 studies | 38% ± 14% | |
adipocyte | 10 studies | 72% ± 17% | |
endothelial cell of lymphatic vessel | 9 studies | 56% ± 22% | |
glutamatergic neuron | 6 studies | 49% ± 17% | |
interneuron | 6 studies | 61% ± 21% | |
cardiac muscle cell | 6 studies | 71% ± 21% | |
ciliated cell | 6 studies | 47% ± 20% | |
type II pneumocyte | 6 studies | 62% ± 22% | |
endothelial cell of vascular tree | 5 studies | 64% ± 32% | |
oligodendrocyte | 5 studies | 33% ± 20% | |
type I pneumocyte | 5 studies | 69% ± 9% | |
cholangiocyte | 4 studies | 65% ± 12% | |
neuron | 4 studies | 49% ± 22% | |
retinal pigment epithelial cell | 4 studies | 56% ± 21% | |
epithelial cell | 4 studies | 50% ± 19% | |
basal cell | 4 studies | 34% ± 13% | |
club cell | 4 studies | 33% ± 7% | |
endothelial cell of sinusoid | 3 studies | 39% ± 7% | |
hepatic stellate cell | 3 studies | 46% ± 15% | |
glomerular endothelial cell | 3 studies | 29% ± 1% | |
GABAergic interneuron | 3 studies | 58% ± 13% | |
Purkinje cell | 3 studies | 66% ± 20% | |
endocardial cell | 3 studies | 51% ± 23% | |
GABAergic amacrine cell | 3 studies | 40% ± 6% | |
retinal ganglion cell | 3 studies | 37% ± 11% | |
rod bipolar cell | 3 studies | 75% ± 31% | |
myeloid cell | 3 studies | 38% ± 12% | |
hepatocyte | 3 studies | 64% ± 20% | |
ependymal cell | 3 studies | 44% ± 16% | |
T cell | 3 studies | 34% ± 20% | |
alveolar macrophage | 3 studies | 46% ± 6% | |
myofibroblast cell | 3 studies | 46% ± 22% | |
respiratory goblet cell | 3 studies | 26% ± 14% | |
melanocyte | 3 studies | 67% ± 36% | |
mesothelial cell | 3 studies | 37% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 100% | 12170.81 | 653 / 653 | 98% | 79.55 | 590 / 605 |
kidney | 100% | 5021.79 | 89 / 89 | 94% | 52.00 | 850 / 901 |
prostate | 100% | 4649.26 | 244 / 245 | 93% | 25.99 | 465 / 502 |
skin | 94% | 5132.48 | 1700 / 1809 | 98% | 50.87 | 462 / 472 |
adrenal gland | 99% | 4174.97 | 256 / 258 | 84% | 40.61 | 194 / 230 |
breast | 100% | 12112.40 | 459 / 459 | 82% | 15.98 | 918 / 1118 |
pancreas | 88% | 1966.15 | 288 / 328 | 94% | 20.89 | 167 / 178 |
brain | 89% | 3181.13 | 2359 / 2642 | 88% | 15.18 | 618 / 705 |
lung | 100% | 11209.54 | 578 / 578 | 67% | 12.10 | 777 / 1155 |
bladder | 100% | 5972.90 | 21 / 21 | 65% | 16.50 | 328 / 504 |
ovary | 100% | 4746.97 | 180 / 180 | 49% | 7.41 | 210 / 430 |
stomach | 100% | 4438.08 | 359 / 359 | 48% | 7.31 | 137 / 286 |
uterus | 99% | 6590.26 | 169 / 170 | 38% | 8.07 | 175 / 459 |
esophagus | 82% | 4539.83 | 1181 / 1445 | 55% | 8.35 | 100 / 183 |
intestine | 98% | 5600.17 | 949 / 966 | 34% | 5.01 | 177 / 527 |
liver | 65% | 1502.52 | 146 / 226 | 54% | 10.31 | 218 / 406 |
adipose | 100% | 13755.64 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 48.13 | 80 / 80 |
spleen | 100% | 3847.27 | 241 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 6399.81 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 100% | 7238.99 | 860 / 861 | 0% | 0 | 0 / 0 |
muscle | 100% | 5470.53 | 802 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 41% | 6.20 | 12 / 29 |
tonsil | 0% | 0 | 0 / 0 | 33% | 5.50 | 15 / 45 |
peripheral blood | 1% | 20.46 | 10 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006470 | Biological process | protein dephosphorylation |
GO_0031175 | Biological process | neuron projection development |
GO_0007165 | Biological process | signal transduction |
GO_0016525 | Biological process | negative regulation of angiogenesis |
GO_0001937 | Biological process | negative regulation of endothelial cell proliferation |
GO_0007156 | Biological process | homophilic cell adhesion via plasma membrane adhesion molecules |
GO_0010596 | Biological process | negative regulation of endothelial cell migration |
GO_0009410 | Biological process | response to xenobiotic stimulus |
GO_0031290 | Biological process | retinal ganglion cell axon guidance |
GO_0010842 | Biological process | retina layer formation |
GO_0005886 | Cellular component | plasma membrane |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0005911 | Cellular component | cell-cell junction |
GO_0005912 | Cellular component | adherens junction |
GO_0005737 | Cellular component | cytoplasm |
GO_0030027 | Cellular component | lamellipodium |
GO_0005001 | Molecular function | transmembrane receptor protein tyrosine phosphatase activity |
GO_0045296 | Molecular function | cadherin binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0016791 | Molecular function | phosphatase activity |
GO_0005515 | Molecular function | protein binding |
GO_0004725 | Molecular function | protein tyrosine phosphatase activity |
Gene name | PTPRM |
Protein name | receptor protein-tyrosine kinase (EC 2.7.10.1) PTPRM protein (Protein tyrosine phosphatase receptor type M) protein-tyrosine-phosphatase (EC 3.1.3.48) Receptor-type tyrosine-protein phosphatase mu (Protein-tyrosine phosphatase mu) (R-PTP-mu) (EC 3.1.3.48) Protein tyrosine phosphatase receptor type M |
Synonyms | PTPRL1 |
Description | FUNCTION: Receptor protein-tyrosine phosphatase that mediates homotypic cell-cell interactions and plays a role in adipogenic differentiation via modulation of p120 catenin/CTNND1 phosphorylation . Promotes CTNND1 dephosphorylation and prevents its cytoplasmic localization where it inhibits SLC2A4 membrane trafficking. In turn, SLC2A4 is directed to the plasma membrane and performs its glucose transporter function . . |
Accessions | ENST00000400053.8 E7EPS8 ENST00000400060.8 J3QRB4 J3KRV2 J3QLI4 ENST00000332175.12 [P28827-1] J3KT55 ENST00000583289.5 ENST00000578916.2 Q49AC9 P28827 ENST00000577468.2 ENST00000583153.2 ENST00000580170.6 [P28827-2] |