CDH15 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CDH15 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CDH15 at tissue level.

III. Associated gene sets

GO_0007043Biological processcell-cell junction assembly
GO_0034332Biological processadherens junction organization
GO_0007275Biological processmulticellular organism development
GO_0007155Biological processcell adhesion
GO_0044331Biological processcell-cell adhesion mediated by cadherin
GO_0007156Biological processhomophilic cell adhesion via plasma membrane adhesion molecules
GO_0016339Biological processcalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO_0000902Biological processcell morphogenesis
GO_0016477Biological processcell migration
GO_0005886Cellular componentplasma membrane
GO_0031594Cellular componentneuromuscular junction
GO_0070062Cellular componentextracellular exosome
GO_0005794Cellular componentGolgi apparatus
GO_0016342Cellular componentcatenin complex
GO_0005912Cellular componentadherens junction
GO_0005901Cellular componentcaveola
GO_0045296Molecular functioncadherin binding
GO_0008013Molecular functionbeta-catenin binding
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCDH15
Protein nameCadherin-15 (Cadherin-14) (Muscle cadherin) (M-cadherin)
SynonymsCDH3
CDH14
DescriptionFUNCTION: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation.

AccessionsENST00000289746.3
P55291