LLGL1 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of LLGL1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2617.05	1444 / 1445	100%	32.80	183 / 183
brain	100%	5364.99	2642 / 2642	100%	87.70	704 / 705
uterus	100%	3599.08	170 / 170	98%	32.09	450 / 459
skin	100%	2989.99	1809 / 1809	98%	31.50	462 / 472
breast	100%	2082.13	459 / 459	97%	21.45	1088 / 1118
intestine	100%	1967.96	965 / 966	96%	17.17	508 / 527
bladder	100%	2313.10	21 / 21	96%	21.40	485 / 504
thymus	99%	1606.73	649 / 653	97%	22.66	584 / 605
stomach	99%	1349.82	354 / 359	97%	19.59	277 / 286
prostate	100%	2161.23	245 / 245	95%	16.33	479 / 502
ovary	100%	3124.02	180 / 180	95%	21.82	408 / 430
lung	97%	1421.48	563 / 578	96%	21.59	1107 / 1155
kidney	100%	1329.39	89 / 89	90%	14.00	811 / 901
adrenal gland	100%	3643.33	258 / 258	84%	13.97	194 / 230
pancreas	83%	654.04	271 / 328	94%	16.11	168 / 178
spleen	100%	1841.91	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	36.24	45 / 45
adipose	100%	1845.47	1199 / 1204	0%	0	0 / 0
blood vessel	100%	1860.44	1329 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	99%	27.05	79 / 80
muscle	98%	1342.68	790 / 803	0%	0	0 / 0
heart	95%	1128.11	822 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	86%	12.65	25 / 29
peripheral blood	50%	406.36	464 / 929	0%	0	0 / 0
liver	16%	110.77	37 / 226	33%	3.95	133 / 406
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0008593	Biological process	regulation of Notch signaling pathway
GO_0065003	Biological process	protein-containing complex assembly
GO_0007409	Biological process	axonogenesis
GO_0006887	Biological process	exocytosis
GO_0006893	Biological process	Golgi to plasma membrane transport
GO_0051294	Biological process	establishment of spindle orientation
GO_0030866	Biological process	cortical actin cytoskeleton organization
GO_0032878	Biological process	regulation of establishment or maintenance of cell polarity
GO_0045197	Biological process	establishment or maintenance of epithelial cell apical/basal polarity
GO_0005856	Cellular component	cytoskeleton
GO_0005886	Cellular component	plasma membrane
GO_0031901	Cellular component	early endosome membrane
GO_0000137	Cellular component	Golgi cis cisterna
GO_0030864	Cellular component	cortical actin cytoskeleton
GO_0032588	Cellular component	trans-Golgi network membrane
GO_0000139	Cellular component	Golgi membrane
GO_0005912	Cellular component	adherens junction
GO_0005737	Cellular component	cytoplasm
GO_0030424	Cellular component	axon
GO_0045159	Molecular function	myosin II binding
GO_0019901	Molecular function	protein kinase binding
GO_0005198	Molecular function	structural molecule activity
GO_0005096	Molecular function	GTPase activator activity
GO_0005515	Molecular function	protein binding

Gene name	LLGL1
Protein name	Lethal(2) giant larvae protein homolog 1 (LLGL) (DLG4) (Hugl-1) (Human homolog to the D-lgl gene protein) LLGL1 protein
Synonyms	HUGL DLG4 HUGL1
Description	FUNCTION: Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells. Involved in axonogenesis through RAB10 activation thereby regulating vesicular membrane trafficking toward the axonal plasma membrane. .
Accessions	A0PJG1 Q15334 ENST00000316843.9

LLGL1 report