LAMA3 | OmnibusX

Name	Number of supported studies	Average coverage
type I pneumocyte	12 studies	60% ± 21%	Explore
basal cell	10 studies	29% ± 20%	Explore
endothelial cell	9 studies	30% ± 11%	Explore
epithelial cell	7 studies	21% ± 4%	Explore
type II pneumocyte	6 studies	31% ± 11%	Explore
smooth muscle cell	5 studies	38% ± 9%	Explore
GABAergic neuron	4 studies	27% ± 7%	Explore
myoepithelial cell	4 studies	42% ± 19%	Explore
endothelial cell of lymphatic vessel	3 studies	20% ± 3%	Explore
interneuron	3 studies	26% ± 8%	Explore

Name	Number of supported studies	Average coverage
lung	3 studies	26% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	99%	2571.20	1428 / 1445	96%	72.87	176 / 183
stomach	96%	3295.71	345 / 359	88%	25.70	253 / 286
intestine	93%	2234.63	902 / 966	89%	25.61	470 / 527
lung	99%	9165.56	575 / 578	82%	37.00	948 / 1155
uterus	100%	7115.21	170 / 170	80%	40.99	366 / 459
bladder	100%	2979.71	21 / 21	64%	25.38	322 / 504
breast	99%	7171.27	456 / 459	62%	13.32	692 / 1118
prostate	100%	4846.01	245 / 245	61%	9.28	307 / 502
ovary	99%	2402.46	179 / 180	61%	14.35	261 / 430
pancreas	26%	301.44	86 / 328	93%	61.11	165 / 178
adipose	100%	4383.07	1201 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	96%	59.46	43 / 45
skin	81%	6596.36	1460 / 1809	8%	0.95	38 / 472
blood vessel	87%	2171.52	1162 / 1335	0%	0	0 / 0
kidney	33%	501.30	29 / 89	48%	9.55	436 / 901
thymus	63%	878.16	410 / 653	10%	1.75	60 / 605
heart	49%	612.60	421 / 861	0%	0	0 / 0
liver	3%	36.06	7 / 226	31%	6.21	126 / 406
brain	24%	266.99	642 / 2642	2%	0.19	15 / 705
adrenal gland	5%	60.26	14 / 258	16%	1.81	37 / 230
muscle	11%	125.71	90 / 803	0%	0	0 / 0
spleen	3%	26.55	7 / 241	0%	0	0 / 0
peripheral blood	1%	10.00	6 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0008544	Biological process	epidermis development
GO_0045995	Biological process	regulation of embryonic development
GO_0035987	Biological process	endodermal cell differentiation
GO_0030334	Biological process	regulation of cell migration
GO_0031581	Biological process	hemidesmosome assembly
GO_0030155	Biological process	regulation of cell adhesion
GO_0098609	Biological process	cell-cell adhesion
GO_0005576	Cellular component	extracellular region
GO_0070062	Cellular component	extracellular exosome
GO_0062023	Cellular component	collagen-containing extracellular matrix
GO_0030056	Cellular component	hemidesmosome
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005912	Cellular component	adherens junction
GO_0005604	Cellular component	basement membrane
GO_0005610	Cellular component	laminin-5 complex
GO_0005608	Cellular component	laminin-3 complex
GO_0005201	Molecular function	extracellular matrix structural constituent
GO_0005102	Molecular function	signaling receptor binding
GO_0005198	Molecular function	structural molecule activity

Gene name	LAMA3
Protein name	LAMA3 protein Laminin subunit alpha 3 HCG1811249, isoform CRA_e (Laminin subunit alpha-3) Alternative protein LAMA3 Laminin alpha-3 chain variant 1 Alpha3A Laminin subunit alpha-3 (Epiligrin 170 kDa subunit) (E170) (Epiligrin subunit alpha) (Kalinin subunit alpha) (Laminin-5 subunit alpha) (Laminin-6 subunit alpha) (Laminin-7 subunit alpha) (Nicein subunit alpha) Laminin subunit alpha-3 HCG1811249, isoform CRA_f (Laminin subunit alpha-3)
Synonyms	LAMNA hCG_1811249
Description	FUNCTION: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.; FUNCTION: Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes.
Accessions	A0A3B3ITG1 ENST00000586751.5 ENST00000587184 A0A0A6YYF2 A0PJJ8 Q566Q1 L8E6V6 B0YJ32 ENST00000585600.5 ENST00000587184.5 [Q16787-4] ENST00000590104.1 Q99533 K7EIP4 K7EQ42 ENST00000592519.1 ENST00000269217.11 [Q16787-1] A0A0A0MSA0 ENST00000588164.2 K7EMU9 A0A075B783 A0A0A0MTS5 K7EPP3 ENST00000313654.14 [Q16787-2] ENST00000588004.1 ENST00000399516.7 [Q16787-3] K7ERM0 ENST00000399516 Q16787 ENST00000269217 ENST00000649721.1

LAMA3 report