Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 7 studies | 38% ± 14% | |
| secretory cell | 5 studies | 23% ± 6% | |
| ciliated cell | 5 studies | 24% ± 6% | |
| squamous epithelial cell | 4 studies | 51% ± 15% | |
| basal cell | 4 studies | 32% ± 18% | |
| club cell | 3 studies | 26% ± 6% | |
| keratinocyte | 3 studies | 27% ± 3% |
Insufficient scRNA-seq data for expression of NECTIN4 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 66% | 1558.89 | 161 / 245 | 96% | 36.45 | 483 / 502 |
| breast | 54% | 1948.02 | 248 / 459 | 97% | 92.28 | 1089 / 1118 |
| bladder | 48% | 2142.52 | 10 / 21 | 83% | 152.89 | 420 / 504 |
| esophagus | 39% | 5620.64 | 558 / 1445 | 81% | 54.89 | 148 / 183 |
| lung | 15% | 224.54 | 85 / 578 | 86% | 77.66 | 999 / 1155 |
| ureter | 0% | 0 | 0 / 0 | 100% | 163.60 | 1 / 1 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 141.77 | 44 / 45 |
| pancreas | 6% | 92.01 | 19 / 328 | 89% | 79.47 | 159 / 178 |
| uterus | 2% | 182.90 | 4 / 170 | 83% | 150.05 | 381 / 459 |
| skin | 72% | 13310.36 | 1305 / 1809 | 6% | 2.34 | 29 / 472 |
| stomach | 23% | 367.03 | 82 / 359 | 44% | 11.45 | 126 / 286 |
| ovary | 0% | 0 | 0 / 180 | 65% | 19.39 | 279 / 430 |
| intestine | 1% | 15.01 | 6 / 966 | 61% | 19.52 | 323 / 527 |
| thymus | 0% | 0 | 0 / 653 | 60% | 26.32 | 366 / 605 |
| kidney | 12% | 204.25 | 11 / 89 | 3% | 2.18 | 28 / 901 |
| liver | 0% | 0 | 0 / 226 | 7% | 5.95 | 28 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.55 | 1 / 29 |
| adipose | 1% | 26.89 | 11 / 1204 | 0% | 0 | 0 / 0 |
| adrenal gland | 0% | 0 | 0 / 258 | 0% | 0.13 | 1 / 230 |
| brain | 0% | 0 | 0 / 2642 | 0% | 0.05 | 2 / 705 |
| muscle | 0% | 2.37 | 1 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 1.46 | 1 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 5.60 | 1 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| GO_0046718 | Biological process | symbiont entry into host cell |
| GO_0007156 | Biological process | homophilic cell adhesion via plasma membrane adhesion molecules |
| GO_0007157 | Biological process | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005912 | Cellular component | adherens junction |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0001618 | Molecular function | virus receptor activity |
| Gene name | NECTIN4 |
| Protein name | Nectin-4 (Ig superfamily receptor LNIR) (Nectin cell adhesion molecule 4) (Poliovirus receptor-related protein 4) [Cleaved into: Processed poliovirus receptor-related protein 4] |
| Synonyms | PVRL4 PRR4 LNIR |
| Description | FUNCTION: Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.; FUNCTION: (Microbial infection) Acts as a receptor for measles virus. . |
| Accessions | Q96NY8 ENST00000368012.4 [Q96NY8-1] |
