RND1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of RND1 at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0007015Biological processactin filament organization
GO_0032956Biological processregulation of actin cytoskeleton organization
GO_0007162Biological processnegative regulation of cell adhesion
GO_0016322Biological processneuron remodeling
GO_0016477Biological processcell migration
GO_0007264Biological processsmall GTPase-mediated signal transduction
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0015629Cellular componentactin cytoskeleton
GO_0005829Cellular componentcytosol
GO_0005912Cellular componentadherens junction
GO_0005886Cellular componentplasma membrane
GO_0005525Molecular functionGTP binding
GO_0019901Molecular functionprotein kinase binding
GO_0005102Molecular functionsignaling receptor binding
GO_0005515Molecular functionprotein binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameRND1
Protein nameRho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
Rho family GTPase 1
SynonymsRHO6
DescriptionFUNCTION: Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments. .

AccessionsENST00000551243.1
H0YHG7
ENST00000309739.6
ENST00000550607.5
Q92730
F8VXU4