VCL report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
fibroblast	35 studies	29% ± 12%	Explore
pericyte	35 studies	37% ± 12%	Explore
smooth muscle cell	31 studies	44% ± 15%	Explore
endothelial cell	26 studies	31% ± 12%	Explore
myofibroblast cell	14 studies	38% ± 13%	Explore
basal cell	12 studies	23% ± 8%	Explore
type I pneumocyte	11 studies	33% ± 9%	Explore
platelet	11 studies	56% ± 18%	Explore
connective tissue cell	11 studies	26% ± 16%	Explore
astrocyte	11 studies	28% ± 11%	Explore
epithelial cell	10 studies	32% ± 18%	Explore
non-classical monocyte	9 studies	25% ± 8%	Explore
capillary endothelial cell	9 studies	22% ± 6%	Explore
adipocyte	9 studies	32% ± 5%	Explore
natural killer cell	8 studies	20% ± 5%	Explore
classical monocyte	8 studies	28% ± 10%	Explore
monocyte	8 studies	23% ± 6%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	19% ± 3%	Explore
megakaryocyte	6 studies	74% ± 16%	Explore
myeloid cell	6 studies	24% ± 1%	Explore
endothelial cell of artery	6 studies	18% ± 2%	Explore
vein endothelial cell	6 studies	24% ± 12%	Explore
retinal cone cell	6 studies	30% ± 11%	Explore
mast cell	6 studies	25% ± 9%	Explore
type II pneumocyte	6 studies	18% ± 2%	Explore
dendritic cell	6 studies	27% ± 14%	Explore
plasmacytoid dendritic cell	6 studies	24% ± 6%	Explore
respiratory goblet cell	5 studies	22% ± 4%	Explore
abnormal cell	5 studies	23% ± 6%	Explore
glutamatergic neuron	5 studies	48% ± 24%	Explore
kidney loop of Henle epithelial cell	5 studies	19% ± 3%	Explore
club cell	5 studies	23% ± 5%	Explore
cardiac muscle cell	5 studies	62% ± 15%	Explore
endothelial cell of vascular tree	5 studies	27% ± 11%	Explore
conventional dendritic cell	4 studies	32% ± 14%	Explore
glial cell	4 studies	21% ± 3%	Explore
microglial cell	4 studies	18% ± 2%	Explore
retinal pigment epithelial cell	4 studies	35% ± 15%	Explore
ciliated cell	4 studies	27% ± 16%	Explore
secretory cell	4 studies	26% ± 5%	Explore
muscle cell	4 studies	52% ± 14%	Explore
GABAergic neuron	4 studies	44% ± 13%	Explore
hepatic stellate cell	3 studies	42% ± 10%	Explore
hematopoietic precursor cell	3 studies	29% ± 9%	Explore
CD8-positive, alpha-beta T cell	3 studies	21% ± 5%	Explore
squamous epithelial cell	3 studies	37% ± 23%	Explore
retinal rod cell	3 studies	22% ± 5%	Explore
endothelial cell of lymphatic vessel	3 studies	27% ± 5%	Explore
ependymal cell	3 studies	30% ± 10%	Explore
Schwann cell	3 studies	30% ± 11%	Explore
transit amplifying cell	3 studies	29% ± 15%	Explore
mesothelial cell	3 studies	28% ± 8%	Explore
gamma-delta T cell	3 studies	17% ± 1%	Explore
myoepithelial cell	3 studies	39% ± 16%	Explore
oligodendrocyte precursor cell	3 studies	21% ± 3%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
lung	9 studies	21% ± 3%	Explore
brain	6 studies	33% ± 19%	Explore
intestine	5 studies	19% ± 4%	Explore
heart	5 studies	33% ± 10%	Explore
eye	4 studies	25% ± 10%	Explore
adipose	4 studies	28% ± 12%	Explore
uterus	3 studies	30% ± 13%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
uterus	100%	37975.83	170 / 170	99%	68.75	455 / 459
intestine	99%	35836.29	961 / 966	100%	62.22	525 / 527
esophagus	99%	33924.51	1428 / 1445	100%	97.99	183 / 183
bladder	100%	38934.62	21 / 21	99%	56.94	497 / 504
breast	100%	14753.89	457 / 459	99%	70.77	1107 / 1118
lung	99%	21320.47	575 / 578	99%	64.19	1144 / 1155
ovary	97%	12868.67	175 / 180	100%	75.76	429 / 430
skin	98%	17112.58	1770 / 1809	96%	39.92	451 / 472
thymus	97%	10667.12	633 / 653	96%	65.35	580 / 605
prostate	96%	22061.82	234 / 245	95%	59.30	479 / 502
stomach	80%	16092.66	286 / 359	99%	73.92	282 / 286
kidney	69%	6478.74	61 / 89	95%	47.20	860 / 901
adrenal gland	37%	2501.49	96 / 258	86%	25.04	197 / 230
pancreas	24%	1511.02	78 / 328	99%	78.07	176 / 178
adipose	100%	18357.03	1204 / 1204	0%	0	0 / 0
blood vessel	100%	52559.56	1335 / 1335	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	36.77	1 / 1
muscle	99%	24099.51	795 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	50.05	44 / 45
heart	93%	20594.26	797 / 861	0%	0	0 / 0
brain	3%	195.87	78 / 2642	86%	25.71	607 / 705
spleen	89%	8541.47	214 / 241	0%	0	0 / 0
eye	0%	0	0 / 0	78%	15.49	62 / 80
liver	6%	413.38	13 / 226	47%	12.97	192 / 406
lymph node	0%	0	0 / 0	52%	11.43	15 / 29
peripheral blood	40%	2890.77	371 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0