Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 14 studies | 31% ± 12% | |
type I pneumocyte | 12 studies | 40% ± 14% | |
epithelial cell | 9 studies | 38% ± 14% | |
goblet cell | 7 studies | 30% ± 16% | |
club cell | 6 studies | 21% ± 4% | |
type II pneumocyte | 6 studies | 25% ± 7% | |
kidney loop of Henle epithelial cell | 5 studies | 24% ± 9% | |
natural killer cell | 4 studies | 27% ± 9% | |
respiratory goblet cell | 4 studies | 25% ± 7% | |
squamous epithelial cell | 4 studies | 42% ± 21% | |
retinal cone cell | 4 studies | 23% ± 3% | |
retinal rod cell | 4 studies | 25% ± 7% | |
basal cell | 4 studies | 26% ± 9% | |
renal principal cell | 4 studies | 26% ± 7% | |
ionocyte | 3 studies | 29% ± 7% | |
secretory cell | 3 studies | 26% ± 6% | |
CD16-positive, CD56-dim natural killer cell, human | 3 studies | 28% ± 8% | |
lymphocyte | 3 studies | 18% ± 2% | |
brush cell | 3 studies | 18% ± 2% | |
enteroendocrine cell | 3 studies | 28% ± 9% | |
oligodendrocyte | 3 studies | 20% ± 4% | |
kidney distal convoluted tubule epithelial cell | 3 studies | 26% ± 7% | |
mucus secreting cell | 3 studies | 29% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
pancreas | 100% | 8220.83 | 328 / 328 | 98% | 79.90 | 175 / 178 |
lung | 100% | 6432.00 | 576 / 578 | 94% | 48.60 | 1080 / 1155 |
liver | 100% | 4251.71 | 226 / 226 | 93% | 35.78 | 377 / 406 |
prostate | 93% | 3879.39 | 229 / 245 | 99% | 35.92 | 496 / 502 |
thymus | 100% | 4706.92 | 653 / 653 | 90% | 26.76 | 544 / 605 |
kidney | 100% | 11681.58 | 89 / 89 | 86% | 30.12 | 776 / 901 |
stomach | 77% | 7538.26 | 278 / 359 | 99% | 100.90 | 282 / 286 |
ovary | 79% | 985.18 | 142 / 180 | 97% | 38.97 | 417 / 430 |
breast | 75% | 2023.95 | 346 / 459 | 97% | 48.07 | 1089 / 1118 |
intestine | 58% | 7446.57 | 561 / 966 | 99% | 111.28 | 520 / 527 |
bladder | 62% | 1611.95 | 13 / 21 | 93% | 65.59 | 469 / 504 |
esophagus | 51% | 3210.44 | 731 / 1445 | 91% | 67.53 | 167 / 183 |
uterus | 51% | 823.01 | 87 / 170 | 88% | 50.88 | 402 / 459 |
adrenal gland | 94% | 1449.67 | 242 / 258 | 13% | 3.70 | 29 / 230 |
spleen | 100% | 5939.01 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 56.29 | 1 / 1 |
tonsil | 0% | 0 | 0 / 0 | 87% | 24.02 | 39 / 45 |
skin | 72% | 4451.82 | 1305 / 1809 | 6% | 0.90 | 28 / 472 |
peripheral blood | 46% | 1124.91 | 424 / 929 | 0% | 0 | 0 / 0 |
adipose | 40% | 441.29 | 479 / 1204 | 0% | 0 | 0 / 0 |
brain | 28% | 443.13 | 740 / 2642 | 1% | 0.11 | 5 / 705 |
blood vessel | 21% | 209.32 | 274 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 10% | 1.35 | 3 / 29 |
heart | 5% | 51.91 | 47 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 1% | 0.20 | 1 / 80 |
muscle | 0% | 3.50 | 3 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0008593 | Biological process | regulation of Notch signaling pathway |
GO_0051301 | Biological process | cell division |
GO_0006887 | Biological process | exocytosis |
GO_0006893 | Biological process | Golgi to plasma membrane transport |
GO_0051294 | Biological process | establishment of spindle orientation |
GO_0030866 | Biological process | cortical actin cytoskeleton organization |
GO_0032878 | Biological process | regulation of establishment or maintenance of cell polarity |
GO_0045197 | Biological process | establishment or maintenance of epithelial cell apical/basal polarity |
GO_0015820 | Biological process | L-leucine transport |
GO_0005886 | Cellular component | plasma membrane |
GO_0030864 | Cellular component | cortical actin cytoskeleton |
GO_0005829 | Cellular component | cytosol |
GO_0005912 | Cellular component | adherens junction |
GO_0005737 | Cellular component | cytoplasm |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0045159 | Molecular function | myosin II binding |
GO_0005096 | Molecular function | GTPase activator activity |
GO_0030165 | Molecular function | PDZ domain binding |
GO_0005515 | Molecular function | protein binding |
Gene name | LLGL2 |
Protein name | LLGL scribble cell polarity complex component 2 LLGL2 protein LLGL scribble cell polarity complex component 2 (HGL) (Lethal(2) giant larvae protein homolog 2) |
Synonyms | |
Description | FUNCTION: Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity. . |
Accessions | ENST00000580925.1 A0PJJ0 ENST00000583658.1 J3KRE1 ENST00000167462.9 [Q6P1M3-2] ENST00000578536.5 J3QLD8 ENST00000578638.5 J3KSD5 J3QRV5 J3QKM6 J3QRZ8 ENST00000578363.5 [Q6P1M3-3] ENST00000581713.5 ENST00000579392.5 ENST00000392550.8 [Q6P1M3-1] ENST00000577200.5 ENST00000578719.1 Q6P1M3 ENST00000375227.8 [Q6P1M3-3] J3QLV4 J3QS20 J3QSA6 ENST00000580578.5 ENST00000583514.5 J3QL58 |