LLGL2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008593Biological processregulation of Notch signaling pathway
GO_0051301Biological processcell division
GO_0006887Biological processexocytosis
GO_0006893Biological processGolgi to plasma membrane transport
GO_0051294Biological processestablishment of spindle orientation
GO_0030866Biological processcortical actin cytoskeleton organization
GO_0032878Biological processregulation of establishment or maintenance of cell polarity
GO_0045197Biological processestablishment or maintenance of epithelial cell apical/basal polarity
GO_0015820Biological processL-leucine transport
GO_0005886Cellular componentplasma membrane
GO_0030864Cellular componentcortical actin cytoskeleton
GO_0005829Cellular componentcytosol
GO_0005912Cellular componentadherens junction
GO_0005737Cellular componentcytoplasm
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0045159Molecular functionmyosin II binding
GO_0005096Molecular functionGTPase activator activity
GO_0030165Molecular functionPDZ domain binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameLLGL2
Protein nameLLGL scribble cell polarity complex component 2
LLGL2 protein
LLGL scribble cell polarity complex component 2 (HGL) (Lethal(2) giant larvae protein homolog 2)
Synonyms
DescriptionFUNCTION: Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity. .

AccessionsENST00000580925.1
A0PJJ0
ENST00000583658.1
J3KRE1
ENST00000167462.9 [Q6P1M3-2]
ENST00000578536.5
J3QLD8
ENST00000578638.5
J3KSD5
J3QRV5
J3QKM6
J3QRZ8
ENST00000578363.5 [Q6P1M3-3]
ENST00000581713.5
ENST00000579392.5
ENST00000392550.8 [Q6P1M3-1]
ENST00000577200.5
ENST00000578719.1
Q6P1M3
ENST00000375227.8 [Q6P1M3-3]
J3QLV4
J3QS20
J3QSA6
ENST00000580578.5
ENST00000583514.5
J3QL58