CDC42EP4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007266Biological processRho protein signal transduction
GO_0008360Biological processregulation of cell shape
GO_0030838Biological processpositive regulation of actin filament polymerization
GO_0031274Biological processpositive regulation of pseudopodium assembly
GO_0071346Biological processcellular response to type II interferon
GO_0015629Cellular componentactin cytoskeleton
GO_0005856Cellular componentcytoskeleton
GO_0005829Cellular componentcytosol
GO_0005912Cellular componentadherens junction
GO_0015630Cellular componentmicrotubule cytoskeleton
GO_0045335Cellular componentphagocytic vesicle
GO_0005886Cellular componentplasma membrane
GO_0012505Cellular componentendomembrane system
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding
GO_0031267Molecular functionsmall GTPase binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameCDC42EP4
Protein nameCDC42 effector protein 4
Cdc42 effector protein 4 (Binder of Rho GTPases 4)
CDC42 effector protein (Rho GTPase binding) 4, isoform CRA_a (cDNA FLJ14479 fis, clone MAMMA1002143, highly similar to Cdc42 effector protein 4 (Binder of Rho GTPases 4)) (cDNA, FLJ92905, Homo sapiens CDC42 effector protein (Rho GTPase binding) 4(CDC42EP4), mRNA)
SynonymshCG_27835
CEP4
BORG4
DescriptionFUNCTION: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts.

AccessionsENST00000580315.1
ENST00000630622.1
ENST00000579611.1
J3QQS6
ENST00000439510.2 [Q9H3Q1-2]
J3QR93
Q9H3Q1
ENST00000335793.4 [Q9H3Q1-1]
ENST00000581014.1
J3KRZ9
B2R6D8