SNAP23 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	28 studies	27% ± 10%	Explore
B cell	26 studies	22% ± 5%	Explore
macrophage	25 studies	24% ± 8%	Explore
non-classical monocyte	20 studies	28% ± 12%	Explore
memory B cell	16 studies	22% ± 5%	Explore
naive B cell	16 studies	21% ± 5%	Explore
monocyte	15 studies	23% ± 6%	Explore
conventional dendritic cell	15 studies	28% ± 11%	Explore
mast cell	14 studies	20% ± 6%	Explore
classical monocyte	14 studies	23% ± 8%	Explore
natural killer cell	12 studies	17% ± 3%	Explore
endothelial cell of lymphatic vessel	12 studies	22% ± 4%	Explore
type I pneumocyte	11 studies	25% ± 8%	Explore
capillary endothelial cell	10 studies	21% ± 3%	Explore
vein endothelial cell	10 studies	24% ± 8%	Explore
platelet	9 studies	47% ± 14%	Explore
endothelial cell of artery	9 studies	23% ± 5%	Explore
dendritic cell	9 studies	27% ± 18%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	19% ± 2%	Explore
fibroblast	8 studies	22% ± 7%	Explore
microglial cell	7 studies	27% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	7 studies	18% ± 3%	Explore
endothelial cell of vascular tree	7 studies	23% ± 5%	Explore
astrocyte	7 studies	28% ± 10%	Explore
oligodendrocyte	7 studies	25% ± 9%	Explore
megakaryocyte	6 studies	60% ± 19%	Explore
leukocyte	6 studies	22% ± 2%	Explore
epithelial cell	6 studies	38% ± 19%	Explore
regulatory T cell	6 studies	18% ± 3%	Explore
plasmacytoid dendritic cell	6 studies	23% ± 8%	Explore
mononuclear phagocyte	5 studies	28% ± 16%	Explore
pericyte	5 studies	18% ± 3%	Explore
myeloid cell	5 studies	28% ± 9%	Explore
cardiac muscle cell	5 studies	31% ± 8%	Explore
abnormal cell	5 studies	21% ± 4%	Explore
GABAergic neuron	5 studies	27% ± 9%	Explore
oligodendrocyte precursor cell	5 studies	31% ± 13%	Explore
goblet cell	5 studies	32% ± 11%	Explore
immature B cell	4 studies	23% ± 6%	Explore
T follicular helper cell	4 studies	17% ± 2%	Explore
glutamatergic neuron	4 studies	39% ± 8%	Explore
basal cell	4 studies	30% ± 9%	Explore
hematopoietic stem cell	4 studies	30% ± 20%	Explore
CD4-positive, alpha-beta T cell	3 studies	18% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	16% ± 1%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	16% ± 0%	Explore
innate lymphoid cell	3 studies	21% ± 6%	Explore
tissue-resident macrophage	3 studies	17% ± 1%	Explore
ciliated cell	3 studies	30% ± 6%	Explore
germinal center B cell	3 studies	38% ± 10%	Explore
muscle cell	3 studies	29% ± 5%	Explore
gamma-delta T cell	3 studies	24% ± 8%	Explore
T cell	3 studies	18% ± 3%	Explore
interneuron	3 studies	32% ± 18%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	10 studies	21% ± 5%	Explore
lung	9 studies	20% ± 4%	Explore
brain	7 studies	31% ± 9%	Explore
heart	4 studies	20% ± 4%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	2122.58	245 / 245	100%	9.79	501 / 502
esophagus	100%	1674.32	1445 / 1445	99%	5.96	182 / 183
lung	100%	2785.31	578 / 578	99%	6.88	1148 / 1155
intestine	100%	2120.61	966 / 966	99%	7.35	521 / 527
stomach	100%	1615.48	359 / 359	98%	7.32	281 / 286
breast	100%	2345.90	459 / 459	98%	8.05	1094 / 1118
thymus	100%	1661.92	652 / 653	96%	6.07	582 / 605
bladder	100%	1952.95	21 / 21	95%	5.66	478 / 504
kidney	100%	1476.28	89 / 89	94%	5.67	846 / 901
skin	100%	1909.43	1808 / 1809	94%	7.96	443 / 472
pancreas	99%	1002.99	326 / 328	94%	6.45	168 / 178
ovary	100%	2093.59	180 / 180	94%	4.42	403 / 430
uterus	100%	2604.22	170 / 170	91%	4.63	417 / 459
brain	94%	707.73	2475 / 2642	95%	4.67	672 / 705
liver	100%	939.12	226 / 226	71%	2.81	290 / 406
adrenal gland	100%	1950.22	258 / 258	54%	1.79	124 / 230
adipose	100%	2505.52	1204 / 1204	0%	0	0 / 0
blood vessel	100%	2969.29	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	10.82	29 / 29
muscle	100%	1868.96	803 / 803	0%	0	0 / 0
spleen	100%	3017.63	241 / 241	0%	0	0 / 0
peripheral blood	99%	3172.53	917 / 929	0%	0	0 / 0
heart	97%	1392.29	839 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	91%	4.68	41 / 45
eye	0%	0	0 / 0	74%	4.03	59 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1