Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 20 studies | 26% ± 6% | |
| astrocyte | 11 studies | 31% ± 13% | |
| type I pneumocyte | 9 studies | 26% ± 8% | |
| oligodendrocyte | 9 studies | 32% ± 10% | |
| ciliated cell | 7 studies | 30% ± 11% | |
| fibroblast | 6 studies | 21% ± 4% | |
| retinal rod cell | 6 studies | 51% ± 21% | |
| epithelial cell | 6 studies | 37% ± 16% | |
| retinal bipolar neuron | 5 studies | 55% ± 10% | |
| adipocyte | 5 studies | 27% ± 6% | |
| Mueller cell | 5 studies | 38% ± 11% | |
| capillary endothelial cell | 4 studies | 19% ± 3% | |
| goblet cell | 4 studies | 22% ± 4% | |
| basal cell | 4 studies | 23% ± 10% | |
| pancreatic A cell | 3 studies | 23% ± 7% | |
| endothelial cell of artery | 3 studies | 17% ± 1% | |
| ON-bipolar cell | 3 studies | 48% ± 23% | |
| respiratory goblet cell | 3 studies | 22% ± 8% | |
| hepatocyte | 3 studies | 48% ± 19% | |
| secretory cell | 3 studies | 22% ± 7% | |
| type II pneumocyte | 3 studies | 21% ± 3% | |
| GABAergic neuron | 3 studies | 22% ± 4% | |
| glutamatergic neuron | 3 studies | 22% ± 5% | |
| oligodendrocyte precursor cell | 3 studies | 20% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 8980.55 | 1445 / 1445 | 61% | 1.30 | 111 / 183 |
| stomach | 100% | 7481.60 | 359 / 359 | 44% | 0.89 | 127 / 286 |
| intestine | 96% | 4679.69 | 927 / 966 | 25% | 0.45 | 130 / 527 |
| thymus | 100% | 9628.09 | 653 / 653 | 12% | 0.17 | 70 / 605 |
| lung | 100% | 11144.53 | 578 / 578 | 11% | 0.22 | 127 / 1155 |
| ovary | 100% | 7722.44 | 180 / 180 | 10% | 0.14 | 43 / 430 |
| pancreas | 97% | 3161.47 | 318 / 328 | 13% | 0.30 | 23 / 178 |
| bladder | 100% | 8621.95 | 21 / 21 | 8% | 0.19 | 41 / 504 |
| kidney | 100% | 6960.89 | 89 / 89 | 8% | 0.14 | 69 / 901 |
| uterus | 99% | 4472.35 | 169 / 170 | 5% | 0.08 | 22 / 459 |
| brain | 96% | 4517.61 | 2532 / 2642 | 8% | 0.12 | 53 / 705 |
| breast | 100% | 8208.32 | 459 / 459 | 2% | 0.07 | 19 / 1118 |
| prostate | 100% | 5309.31 | 245 / 245 | 1% | 0.02 | 4 / 502 |
| liver | 100% | 6593.23 | 226 / 226 | 0% | 0.01 | 2 / 406 |
| adipose | 100% | 11011.98 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 9764.65 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| skin | 99% | 7305.60 | 1792 / 1809 | 0% | 0 | 0 / 472 |
| heart | 98% | 4594.25 | 841 / 861 | 0% | 0 | 0 / 0 |
| adrenal gland | 90% | 3610.60 | 233 / 258 | 0% | 0 | 0 / 230 |
| muscle | 63% | 1365.17 | 504 / 803 | 0% | 0 | 0 / 0 |
| spleen | 34% | 585.43 | 81 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 21% | 1678.37 | 191 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.03 | 1 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0046037 | Biological process | GMP metabolic process |
| GO_0046710 | Biological process | GDP metabolic process |
| GO_0090559 | Biological process | regulation of membrane permeability |
| GO_0045216 | Biological process | cell-cell junction organization |
| GO_0034109 | Biological process | homotypic cell-cell adhesion |
| GO_0050892 | Biological process | intestinal absorption |
| GO_0035633 | Biological process | maintenance of blood-brain barrier |
| GO_0090557 | Biological process | establishment of endothelial intestinal barrier |
| GO_0150105 | Biological process | protein localization to cell-cell junction |
| GO_1905605 | Biological process | positive regulation of blood-brain barrier permeability |
| GO_0098609 | Biological process | cell-cell adhesion |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0044291 | Cellular component | cell-cell contact zone |
| GO_0005829 | Cellular component | cytosol |
| GO_0005912 | Cellular component | adherens junction |
| GO_0005923 | Cellular component | bicellular tight junction |
| GO_0005634 | Cellular component | nucleus |
| GO_0019904 | Molecular function | protein domain specific binding |
| GO_0045296 | Molecular function | cadherin binding |
| GO_1990782 | Molecular function | protein tyrosine kinase binding |
| GO_0004385 | Molecular function | guanylate kinase activity |
| GO_0030674 | Molecular function | protein-macromolecule adaptor activity |
| GO_0044325 | Molecular function | transmembrane transporter binding |
| GO_0050839 | Molecular function | cell adhesion molecule binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | TJP2 |
| Protein name | Tight junction protein ZO-2 (Tight junction protein 2) (Zona occludens protein 2) (Zonula occludens protein 2) Tight junction protein 2 Alternative protein TJP2 |
| Synonyms | X104 ZO2 |
| Description | FUNCTION: Plays a role in tight junctions and adherens junctions (By similarity). Acts as a positive regulator of RANKL-induced osteoclast differentiation, potentially via mediating downstream transcriptional activity (By similarity). . |
| Accessions | L8EAC1 B1AN86 ENST00000648402.1 ENST00000348208.9 [Q9UDY2-2] U3KQJ2 ENST00000650333.1 A0A3B3ISZ5 ENST00000423935.6 A0A3B3ITE1 A0A3B3IU51 ENST00000377245.9 [Q9UDY2-1] ENST00000649114.1 A0A3B3ISF1 A0A3B3IS03 ENST00000636438.1 ENST00000539225.2 [Q9UDY2-7] A0A3B3IRI3 ENST00000606364.5 A0A3B3IT83 ENST00000650460.1 ENST00000648042.1 ENST00000649134.1 A0A1B0GTW1 ENST00000649943.1 A0A3B3IU26 ENST00000649939.1 ENST00000647986.1 A0A3B3IRV6 Q9UDY2 ENST00000650084.1 ENST00000535702.6 [Q9UDY2-6] |