Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 27 studies | 36% ± 13% | |
oligodendrocyte | 15 studies | 50% ± 17% | |
astrocyte | 12 studies | 29% ± 13% | |
macrophage | 12 studies | 29% ± 11% | |
ciliated cell | 11 studies | 33% ± 13% | |
fibroblast | 10 studies | 25% ± 6% | |
microglial cell | 9 studies | 29% ± 12% | |
smooth muscle cell | 9 studies | 30% ± 9% | |
epithelial cell | 8 studies | 36% ± 15% | |
myeloid cell | 8 studies | 34% ± 21% | |
pericyte | 7 studies | 30% ± 8% | |
plasmacytoid dendritic cell | 6 studies | 24% ± 6% | |
B cell | 5 studies | 20% ± 4% | |
dendritic cell | 5 studies | 23% ± 3% | |
endothelial cell of artery | 5 studies | 31% ± 13% | |
vein endothelial cell | 5 studies | 41% ± 27% | |
capillary endothelial cell | 5 studies | 24% ± 6% | |
endothelial cell of lymphatic vessel | 5 studies | 27% ± 7% | |
squamous epithelial cell | 4 studies | 38% ± 20% | |
retinal pigment epithelial cell | 4 studies | 46% ± 19% | |
Mueller cell | 4 studies | 35% ± 9% | |
endothelial cell of vascular tree | 4 studies | 46% ± 25% | |
monocyte | 4 studies | 24% ± 10% | |
type II pneumocyte | 4 studies | 21% ± 4% | |
basal cell | 4 studies | 35% ± 26% | |
mesothelial cell | 4 studies | 32% ± 17% | |
conventional dendritic cell | 3 studies | 22% ± 6% | |
glial cell | 3 studies | 27% ± 6% | |
mast cell | 3 studies | 24% ± 5% | |
lymphocyte | 3 studies | 17% ± 2% | |
myofibroblast cell | 3 studies | 23% ± 5% | |
hepatocyte | 3 studies | 61% ± 19% | |
alveolar macrophage | 3 studies | 42% ± 8% | |
type I pneumocyte | 3 studies | 21% ± 2% | |
Schwann cell | 3 studies | 39% ± 17% | |
brush cell | 3 studies | 31% ± 2% | |
renal principal cell | 3 studies | 54% ± 17% | |
mucus secreting cell | 3 studies | 32% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
intestine | 100% | 4070.85 | 966 / 966 | 100% | 38.24 | 527 / 527 |
stomach | 100% | 2333.83 | 359 / 359 | 100% | 37.24 | 286 / 286 |
esophagus | 100% | 3178.03 | 1444 / 1445 | 100% | 43.54 | 183 / 183 |
kidney | 100% | 4066.85 | 89 / 89 | 99% | 31.79 | 892 / 901 |
skin | 100% | 6052.02 | 1808 / 1809 | 99% | 36.41 | 467 / 472 |
uterus | 100% | 4178.36 | 170 / 170 | 98% | 31.84 | 451 / 459 |
lung | 99% | 2762.77 | 575 / 578 | 99% | 27.13 | 1138 / 1155 |
breast | 100% | 3132.00 | 459 / 459 | 98% | 21.81 | 1091 / 1118 |
thymus | 100% | 2157.65 | 651 / 653 | 98% | 19.51 | 591 / 605 |
prostate | 99% | 2798.29 | 243 / 245 | 98% | 20.77 | 492 / 502 |
bladder | 100% | 3207.43 | 21 / 21 | 96% | 25.55 | 484 / 504 |
liver | 100% | 2614.20 | 225 / 226 | 84% | 18.18 | 343 / 406 |
ovary | 91% | 1506.26 | 164 / 180 | 90% | 10.86 | 387 / 430 |
pancreas | 77% | 972.21 | 251 / 328 | 98% | 43.33 | 174 / 178 |
brain | 49% | 873.91 | 1299 / 2642 | 85% | 11.80 | 596 / 705 |
adrenal gland | 56% | 594.43 | 145 / 258 | 50% | 5.34 | 114 / 230 |
blood vessel | 100% | 6892.96 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 1892.97 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 30.86 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 24.04 | 1 / 1 |
adipose | 100% | 4078.39 | 1203 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 33.37 | 79 / 80 |
lymph node | 0% | 0 | 0 / 0 | 97% | 21.45 | 28 / 29 |
muscle | 70% | 955.18 | 565 / 803 | 0% | 0 | 0 / 0 |
heart | 70% | 884.50 | 601 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 19% | 2516.26 | 180 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006897 | Biological process | endocytosis |
GO_0001701 | Biological process | in utero embryonic development |
GO_0003094 | Biological process | glomerular filtration |
GO_0001570 | Biological process | vasculogenesis |
GO_0032836 | Biological process | glomerular basement membrane development |
GO_0048008 | Biological process | platelet-derived growth factor receptor signaling pathway |
GO_0035166 | Biological process | post-embryonic hemopoiesis |
GO_0007015 | Biological process | actin filament organization |
GO_0072015 | Biological process | podocyte development |
GO_0032835 | Biological process | glomerulus development |
GO_0005903 | Cellular component | brush border |
GO_0005902 | Cellular component | microvillus |
GO_0005856 | Cellular component | cytoskeleton |
GO_0005886 | Cellular component | plasma membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0032437 | Cellular component | cuticular plate |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0005912 | Cellular component | adherens junction |
GO_0005737 | Cellular component | cytoplasm |
GO_0045334 | Cellular component | clathrin-coated endocytic vesicle |
GO_0016459 | Cellular component | myosin complex |
GO_0051015 | Molecular function | actin filament binding |
GO_0035091 | Molecular function | phosphatidylinositol binding |
GO_0000146 | Molecular function | microfilament motor activity |
GO_0005524 | Molecular function | ATP binding |
GO_0005516 | Molecular function | calmodulin binding |
GO_0005515 | Molecular function | protein binding |
GO_0016887 | Molecular function | ATP hydrolysis activity |
Gene name | MYO1E |
Protein name | MYO1E variant protein (Myosin IE) Myosin IE Unconventional myosin-Ie (Myosin-Ic) (Unconventional myosin 1E) |
Synonyms | hCG_38672 MYO1C |
Description | FUNCTION: Actin-based motor molecule with ATPase activity . Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain. Involved in clathrin-mediated endocytosis and intracellular movement of clathrin-coated vesicles . Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via ARL14EP and ARL14. . |
Accessions | H0YNB0 H0YLJ4 ENST00000559269.5 ENST00000558571.1 Q4KMR3 ENST00000559412.1 H0YNQ8 Q12965 ENST00000288235.9 H0YLE5 H0YN00 ENST00000559489.1 ENST00000560749.1 |