Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 19 studies | 45% ± 15% | |
| deuterosomal cell | 4 studies | 36% ± 2% | |
| astrocyte | 4 studies | 36% ± 8% | |
| epithelial cell | 3 studies | 24% ± 2% | |
| retinal rod cell | 3 studies | 17% ± 1% | |
| GABAergic neuron | 3 studies | 32% ± 9% | |
| glutamatergic neuron | 3 studies | 54% ± 4% | |
| ependymal cell | 3 studies | 52% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 1047.94 | 653 / 653 | 88% | 2.02 | 531 / 605 |
| kidney | 100% | 683.25 | 89 / 89 | 81% | 1.95 | 732 / 901 |
| ovary | 100% | 580.14 | 180 / 180 | 75% | 1.64 | 324 / 430 |
| breast | 100% | 446.37 | 459 / 459 | 67% | 1.26 | 751 / 1118 |
| brain | 92% | 388.40 | 2428 / 2642 | 75% | 1.51 | 529 / 705 |
| prostate | 100% | 545.69 | 245 / 245 | 61% | 0.84 | 305 / 502 |
| pancreas | 95% | 224.53 | 313 / 328 | 60% | 0.96 | 107 / 178 |
| adrenal gland | 98% | 346.33 | 252 / 258 | 47% | 0.68 | 107 / 230 |
| lung | 99% | 545.08 | 570 / 578 | 43% | 0.80 | 497 / 1155 |
| uterus | 100% | 742.21 | 170 / 170 | 37% | 0.85 | 172 / 459 |
| skin | 95% | 257.82 | 1713 / 1809 | 35% | 0.55 | 164 / 472 |
| bladder | 100% | 458.38 | 21 / 21 | 24% | 0.35 | 119 / 504 |
| stomach | 97% | 339.57 | 347 / 359 | 12% | 0.17 | 35 / 286 |
| esophagus | 86% | 384.72 | 1249 / 1445 | 22% | 0.36 | 41 / 183 |
| intestine | 91% | 423.49 | 878 / 966 | 13% | 0.19 | 66 / 527 |
| blood vessel | 100% | 414.70 | 1331 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 100% | 1152.11 | 800 / 803 | 0% | 0 | 0 / 0 |
| adipose | 99% | 355.43 | 1193 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 99% | 230.40 | 238 / 241 | 0% | 0 | 0 / 0 |
| heart | 95% | 311.50 | 822 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 16% | 0.21 | 13 / 80 |
| liver | 5% | 6.56 | 11 / 226 | 9% | 0.15 | 35 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.13 | 2 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 7% | 0.12 | 3 / 45 |
| peripheral blood | 6% | 8.15 | 58 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0090251 | Biological process | protein localization involved in establishment of planar polarity |
| GO_0048515 | Biological process | spermatid differentiation |
| GO_0007165 | Biological process | signal transduction |
| GO_0060041 | Biological process | retina development in camera-type eye |
| GO_1903348 | Biological process | positive regulation of bicellular tight junction assembly |
| GO_0030030 | Biological process | cell projection organization |
| GO_0030036 | Biological process | actin cytoskeleton organization |
| GO_0098609 | Biological process | cell-cell adhesion |
| GO_0007632 | Biological process | visual behavior |
| GO_0005856 | Cellular component | cytoskeleton |
| GO_0032391 | Cellular component | photoreceptor connecting cilium |
| GO_0016020 | Cellular component | membrane |
| GO_0031514 | Cellular component | motile cilium |
| GO_0005911 | Cellular component | cell-cell junction |
| GO_0005929 | Cellular component | cilium |
| GO_0005829 | Cellular component | cytosol |
| GO_0005912 | Cellular component | adherens junction |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005923 | Cellular component | bicellular tight junction |
| GO_0005198 | Molecular function | structural molecule activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | NPHP1 |
| Protein name | Nephrocystin 1 (Nephronophthisis 1 (Juvenile), isoform CRA_g) Nephrocystin 1 (Nephronophthisis 1 (Juvenile), isoform CRA_e) Nephrocystin 1 Nephrocystin-1 (Juvenile nephronophthisis 1 protein) |
| Synonyms | NPH1 hCG_1988612 |
| Description | FUNCTION: Together with BCAR1 it may play a role in the control of epithelial cell polarity (By similarity). Involved in the organization of apical junctions in kidney cells together with NPHP4 and RPGRIP1L/NPHP8 (By similarity). Does not seem to be strictly required for ciliogenesis (By similarity). Seems to help to recruit PTK2B/PYK2 to cell matrix adhesions, thereby initiating phosphorylation of PTK2B/PYK2 and PTK2B/PYK2-dependent signaling (By similarity). May play a role in the regulation of intraflagellar transport (IFT) during cilia assembly. Required for normal retina development (By similarity). In connecting photoreceptor cilia influences the movement of some IFT proteins such as IFT88 and WDR19. Involved in spermatogenesis (By similarity). . |
| Accessions | A0A6Q8PH10 ENST00000316534.8 [O15259-4] ENST00000417665.5 ENST00000445609.7 [O15259-2] H7C014 H7C2K4 A0A6Q8PHS3 ENST00000676053.1 [O15259-3] C9JNM7 ENST00000676028.1 ENST00000675067.1 ENST00000355301.8 [O15259-3] ENST00000449600.1 ENST00000393272.7 [O15259-1] ENST00000422492.1 C9J082 ENST00000674677.1 ENST00000676091.1 A0A6Q8PGI7 ENST00000418527.1 O15259 A0A6Q8PHD4 |
